Results 61 to 70 of about 144,330 (264)

Deformation and Resistivity Characteristics of Compacted Loess Under Dry–Wet Cycles

Geosciences
Compacted loess is widely used as road subgrade filling in northwestern China, but its stability is threatened by traffic loads and repeated dry–wet cycles, leading to subgrade settlement or collapse.
Peng Li, Zichuan Wang, Yuqi Liu, Jiaxin Yang, Xiao Zhang, Zemin Xue, Dongtun Hao, Pengju Qin   +7 more
doaj   +1 more source

Compressibilidade de um Argissolo sob plantio direto escarificado e compactado Compressibility of a Paleudalf chisel plough and compacted under no-tillage

Ciência Rural, 2006
A compressibilidade do solo é dependente do tipo, da intensidade, da freqüência da força aplicada por máquinas agrícolas e dos sistemas de manejo adotados.
Cláudia Liane Rodrigues de Lima, Dalvan Jose Reinert, José Miguel Reichert, Luis Eduardo Akiyoshi Sanches Suzuki   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

On the use of constrained modulus for soil settlement analysis

Magazine of Civil Engineering
Soil settlement is a key parameter in engineering design of geotechnical structures. Two approaches have been used for the characterization of soil behaviour under one dimensional compression: the linear - nonlinear, the traditional approach, and the ...
Al-Moadhen Muataz Muayad, Abdullah Murtatha M, Oleiwi Mohammed S   +2 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Sustainable prediction of compression index in fine-grained soils using machine learning techniques

Open Geosciences
The accurate prediction of ultimate settlement is of critical importance for the longevity of structures, as it helps prevent structural damage and functional deterioration.
İmamoğlu Tuncay, Sert Sedat, Bol Ertan, Özocak Aşkın, Arslan Eylem, Bağca İrem, Kocaman Kadir, Özsağır Mustafa, Akmaz Emre   +8 more
doaj   +1 more source

Impact of rock content and fine-grained soil properties on the compressive deformation behavior of soil-rock mixtures

Frontiers in Earth Science
Soil-rock mixtures are extensively used in geotechnical engineering applications, such as embankment construction, dam engineering, and slope reinforcement, where their compressive deformation characteristics play a crucial role in influencing the ...
Jian Gong, Jian Gong, Jianfeng Wang, Shiting Zhang, Yuxing Xing, Liangbin Deng, Zhengliang Long, Xianwei Pang, Mingjie Jiang   +8 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source