Results 51 to 60 of about 142,687 (264)

Compression Index Regression of Fine-Grained Soils with Machine Learning Algorithms

Applied Sciences
Soil consolidation, particularly in fine-grained soils like clay, is crucial in predicting settlement and ensuring the stability of structures.
Mintae Kim, Muharrem A. Senturk, Liang Li   +2 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Approximate String Matching with Compressed Indexes [PDF]

Algorithms, 2009
A compressed full-text self-index for a text T is a data structure requiring reduced space and able to search for patterns P in T. It can also reproduce any substring of T, thus actually replacing T. Despite the recent explosion of interest on compressed indexes, there has not been much progress on functionalities beyond the basic exact search. In this
Luís M. S. Russo, Gonzalo Navarro 0001, Arlindo L. Oliveira, Pedro Morales   +3 more
openaire   +4 more sources

Case Study on Analysis of Soil Compression Index Prediction Performance Using Linear and Regularized Linear Machine Learning Models (In Korea)

Applied Sciences
The compression index (Cc) is a critical soil parameter that is used to estimate the consolidation settlement of ground. In this study, the compression index, typically obtained through consolidation tests, was predicted using machine learning techniques
Seungyeon Ryu, Jin Kim, Hyoyeop Choi, Jongyoung Lee, Junggeun Han   +4 more
doaj   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

FEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino, Giuliana Fusco, Alfonso De Simone   +2 more
wiley   +1 more source

Compressed Indexing with Signature Grammars [PDF]

, 2018
The compressed indexing problem is to preprocess a string $S$ of length $n$ into a compressed representation that supports pattern matching queries. That is, given a string $P$ of length $m$ report all occurrences of $P$ in $S$. We present a data structure that supports pattern matching queries in $O(m + occ (\lg\lg n + \lg^εz))$ time using $O(z \lg(n /
Christiansen, Anders Roy, Ettienne, Mikko Berggren   +1 more
openaire   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Theoretical study on the application of isothermal compression technology in vapor‐compression refrigeration systems with an isothermal piston

Energy Science & Engineering, 2021
Vapor‐compression refrigeration systems are widely used in refrigeration equipment. Theoretically, the process is typically divided into two isobaric processes: an adiabatic isentropic compression process and adiabatic isentropic throttling process.
Yu Hu, Weiqing Xu, Teng Ren, Maolin Cai, Bo Yang, Yan Shi   +5 more
doaj   +1 more source