Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney +4 more
wiley +1 more source
Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière +6 more
wiley +1 more source
Fluorescein Angiography for Monitoring Neural Blood Flow in Chronic Nerve Compression Neuropathy: Experimental Animal Models and Preliminary Clinical Observations. [PDF]
Saito K +4 more
europepmc +1 more source
Abstract figure legend Calmodulin (CaM) is a ubiquitous calcium (Ca2+) sensor that translates intracellular Ca2+ signals into modulation of hundreds of effector proteins including ion channels. CaM is increasingly recognized as a key regulator of the transient receptor potential (TRP) channel family, yet the underlying ‘calmodulation playbook’ is only ...
Aden M. Alemayhu, Candice E. Paulsen
wiley +1 more source
Reduced Fascicle Area Demonstrated in Ilioinguinal Nerves Resected from Primary Inguinal Herniorrhaphy Patients as Evidence of Compression Neuropathy. [PDF]
Wright R +6 more
europepmc +1 more source
Sight-threatening optic neuropathy is associated with paranasal lymphoma
Takahiko Hayashi1, Ken Watanabe2, Yukio Tsuura3, Gengo Tsuji4, Shingo Koyama4, Jun Yoshigi4, Naoko Hirata1, Shin Yamane1, Yasuhito Iizima5, Shigeo Toyota6, Satoshi Takeuchi11Department of Ophthalmology, Yokosuka Kyosai Hospital, Japan; 2Department of ...
Yukio Tsuura +3 more
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Schwann Cell‐Specific ATG7‐Dependent Autophagy Protects Myelin in a Mouse Model of Krabbe Disease
Krabbe disease (KD) is caused by mutations in GALC and deregulated lysosomal function in Schwann cells (SCs). Using a SC‐specific Galc‐cKO mouse, we identified altered autophagy in SCs during KD progression. Further ablation of Atg7 in SCs of KD worsened disease severity.
Narayan Dhimal +8 more
wiley +1 more source
Relationship of obesity indices with clinical severity and nerve conduction studies in females presenting with median nerve compression neuropathy at the wrist. [PDF]
Salamh F +5 more
europepmc +1 more source
Fundamental Data Compression provides all the information students need to be able to use this essential technology in their future careers. A huge, active research field, and a part of many people's everyday lives, compression technology is an essential
Pu, Ida Mengyi., Pu, Ida
core
Acute Neurological Events in Children With Hemoglobin SC Disease: A Multicenter Retrospective Study
ABSTRACT Introduction Neurological manifestations in children with hemoglobin SC (HbSC) disease remain insufficiently characterized, particularly regarding acute events. The aim of this study was to describe the spectrum and frequency of acute neurological events in a multicenter cohort of children with HbSC disease.
Célia Paulmin +11 more
wiley +1 more source

