Results 171 to 180 of about 26,973 (290)
Experimental Physiology, EarlyView.Abstract Chronic low‐grade inflammation characterizes type 2 diabetes mellitus (T2DM) and underlies the development of peripheral neuropathy, symptoms of which include mechanical allodynia and an exaggerated exercise pressor reflex. The purpose of this study was to determine whether mechanical allodynia and/or specific concentrations of inflammatory ...
Michelle L. Harrison +8 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney +4 more
wiley +1 more source
Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation
The Journal of Physiology, EarlyView.Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson +7 more
wiley +1 more source
The role of the sympathetic nervous system in the pathomechanism and the therapy of hypertension
, 2014 Légrády Péter
core
Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes
The Journal of Physiology, EarlyView.Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière +6 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Calmodulin (CaM) is a ubiquitous calcium (Ca2+) sensor that translates intracellular Ca2+ signals into modulation of hundreds of effector proteins including ion channels. CaM is increasingly recognized as a key regulator of the transient receptor potential (TRP) channel family, yet the underlying ‘calmodulation playbook’ is only ...
Aden M. Alemayhu, Candice E. Paulsen
wiley +1 more source
Wavelet‐Based Hurst Exponent Estimation
WIREs Computational Statistics, Volume 18, Issue 3, September 2026.The review explores how wavelet‐based methods for estimating the Hurst parameters have developed from their theoretical roots to real‐world applications in fields like biology, engineering, and telecommunications. The review aims to highlight key techniques, compare their strengths and limitations, and point out challenges that still need to be ...
Dixon Vimalajeewa +2 more
wiley +1 more source
eFood, Volume 7, Issue 4, August 2026.A ratiometric fluorescent nanosensor, comprising biomass‐derived iron‐doped carbon dots as the probe and silver nanoclusters as the internal reference, was immobilized onto a polyvinyl alcohol nanofiber membrane via electrospinning. A deep learning model, integrated into a smartphone application, accurately quantified chlorpyrifos by analyzing images ...
Weirui Fang +7 more
wiley +1 more source
Glia, Volume 74, Issue 8, August 2026.Using [18F]‐SMBT‐1 PET, we longitudinally tracked MAO‐B–expressing reactive astrocytes during orofacial neuropathic pain development in rats, revealing region‐ and time‐specific astrocyte activation during pain chronification. ABSTRACT Chronic neuropathic pain represents a significant global health burden and is hypothesized to be maintained by an ...
Lewis S. Crawford +14 more
wiley +1 more source