Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
The main purpose of this paper is to determine the fine spectrum with respect to Goldberg's classification of the operator defined by the lambda matrix over the sequence spaces and c.
Medine Yeşilkayagil, Feyzi Başar
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
An integral operator on the classes \(\mathcal{S}^{\ast}(\alpha )\) and \(\mathcal{CVH}(\beta )\) [PDF]
The purpose of this paper is to study some properties related to convexity order and coefficients estimation for a general integral operator. We find the convexity order for this operator, using the analytic functions from the class of starlike functions
Ularu, Nicoleta, Breaz, Nicoleta
core +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Hardware architecture for lossless image compression based on context-based modeling and arithmetic coding [PDF]
In this paper we present a novel hardware architecture for context-based statistical lossless image compression, as part of a dynamically reconfigurable architecture for universal lossless compression.
Vitulli, Raffaele +7 more
core +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
Spectral analysis of second order quantum difference operator over the sequence space lp (1 < p < ∞)
In this article, we study the spectrum, fine spectrum and boundedness property of second order quantum difference operator ∆2q (0 < q < 1) over the class of sequence lp (1 < p < ∞), the pth summable sequence space.
N. Kalita, A.J. Dutta
doaj +1 more source
Preprocessing operations and the reverse compression
The task of compression of data -- as stated by the source coding theorem -- is one of the cornerstones of information theory. Data compression usually exploits statistical redundancies in the data according to its prior distribution. Motivated by situations where one does not have access to the statistics of data, but has some information about a ...
Capela, Matheus, Costa, Fabio
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source

