Results 101 to 110 of about 1,858,322 (315)

An acoustic signature of extreme failure on model granular materials

Scientific Reports, 2022
Unexpectedly, granular materials can fail, the structure even destroyed, spontaneously in simple isotropic compression with stick-slip-like frictional behaviour.
T. T. T. Nguyên, T. Doanh, A. Le Bot, D. Dalmas   +3 more
doaj   +1 more source

A hardware implementation of Region-of-Interest selection in LAr-TPC for data reduction and triggering

, 2010
Large Liquid Argon TPC detectors in the range of multikton mass for neutrino and astroparticle physics require the extraction and treatment of signals from some 105 wires.
A Fava, A Guglielmi, B Baibussinov, B. Baibussinov ., C Farnese, C Rubbia, D Dequal, D Gibin, D. Angeli ., E Scantamburlo, F Pietropaolo, F Varanini, G Meng, ICARUS collaboration, K Cieslik, S Centro, S Ventura   +16 more
core   +1 more source

Long‐Term Evaluation of Givinostat in Duchenne Muscular Dystrophy, and Natural History Comparisons

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This ongoing, open‐label extension study is evaluating the long‐term safety, tolerability, and efficacy of givinostat, a Class I and II histone deacetylase inhibitor, in patients with Duchenne muscular dystrophy (DMD). Methods The recruited patients completed one of two prior clinical studies (one Phase 2 and one Phase 3 [EPIDYS ...
Craig M. McDonald, Michela Guglieri, Dragana Vučinić, Gyula Acsadi, John F. Brandsema, Claudio Bruno, Erika L. Finanger, Amy Harper, Mercedes Lopez Lobato, Riccardo Masson, Nuria Muelas, Francina Munell, Yoram Nevo, Yann Péréon, Han Phan, Valeria A. Sansone, Mariacristina Scoto, Tracey Willis, Richard S. Finkel, Krista Vandenborne, Sara Cazzaniga, Silvia Montrasio, Federica Alessi, Paolo Bettica, Eugenio Mercuri, for the Givinostat Study 51 Investigators, the Cooperative International Neuromuscular Research Group (CINRG) Duchenne Natural History Study (DNHS) Investigators, the ImagingDMD Investigators, Enrico Bertini, Giacomo Pietro Comi, Eugenio Maria Mercuri, Giuseppe Vita, Sonia Messina, Claudio Bruno, Riccardo Masson, Valeria Sansone, Nathalie Goemans, Liesbeth De Waele, Laurent Servais, Teresa Gidaro, Odile Boespflug‐Tanguy, Yann Péréon, Jessika Johannsen, Astrid Blaschek, Ulrike Schara‐Schmidt, Erik Niks, Imelda de Groot, Saskia Houwen‐van Opstal, Andres Nascimento, Juan Jesus Vilchez, Nuria Muelas, Francina Munell, Marcos Madruga Garrido, Mercedes Lopez Lobato, Michaela Guglieri, Tracey Willis, Stefan Spinty, Daniel Hawcutt, Mariacristina Scoto, Jean K. Mah, Laura McAdam, Kathryn Selby, Katherine Mathews, Craig McDonald, Craig Zaidman, Barry Byrne, John Brandsema, Gyula Acsadi, Chamindra Laverty, Amy Harper, Erika Finanger, Han Phan, Yoram Nevo, Vedrana Milic Rasic, Dragana Vucinic   +74 more
wiley   +1 more source

muCool: A novel low-energy muon beam for future precision experiments

, 2019
Experiments with muons ($\mu^{+}$) and muonium atoms ($\mu^{+}e^{-}$) offer several promising possibilities for testing fundamental symmetries. Examples of such experiments include search for muon electric dipole moment, measurement of muon $g-2$ and ...
Antognini, A., Bao, Y., Belosevic, I., Eggenberger, A., Hildebrandt, M., Iwai, R., Kaplan, D. M., Khaw, K. S., Kirch, K., Knecht, A., Papa, A., Petitjean, C., Phillips, T. J., Piegsa, F. M., Ritjoho, N., Stoykov, A., Taqqu, D., Wichmann, G.   +17 more
core   +1 more source

Compressive sensing as a paradigm for building physics models [PDF]

Physical Review B, 2013
The widely accepted intuition that the important properties of solids are determined by a few key variables underpins many methods in physics. Though this reductionist paradigm is applicable in many physical problems, its utility can be limited because the intuition for identifying the key variables often does not exist or is difficult to develop ...
Fei Zhou, Vidvuds Ozoliņš, Lance J. Nelson, Gus L. W. Hart   +3 more
openaire   +2 more sources

Interleukin‐6 as a Key Biomarker in Facioscapulohumeral Dystrophy: Evidence From Longitudinal Analyses

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini, Emanuela Martinuzzi, Sandra Dhifallah, Abderhmane Slioui, Angela Puma, Luisa Villa, Michele Cavalli, Andra Ezaru, Jérémy Garcia, Manuela Gambella, Federico Torre, Luca Jacopo Pavan, Nicolas Glaichenhaus, Sabrina Sacconi   +13 more
wiley   +1 more source

Advanced numerical studies of the neutralized drift compression of intense ion beam pulses

Physical Review Special Topics. Accelerators and Beams, 2007
Longitudinal bunch compression of intense ion beams for warm dense matter and heavy ion fusion applications occurs by imposing an axial velocity tilt onto an ion beam across the acceleration gap of a linear induction accelerator, and subsequently ...
Adam B. Sefkow, Ronald C. Davidson
doaj   +1 more source

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas, Pablo Iruzubieta, Alberto Damborenea, Laura Pérez‐Fernández, Inmaculada Azorín, Juan Carlos Jiménez García, Ana Töpf, Pilar Martí, Lorena Fores‐Toribio, María Manterola, Rosana Blanco‐Mañez, Oihane Pikatza‐Menoio, Sonia Alonso‐Martín, Volker Straub, Aitziber L. Cortajarena, Adolfo López de Munain, David De Sancho, Lorea Blázquez, Juan J. Vilchez   +18 more
wiley   +1 more source

Dynamic convergent shock compression initiated by return current in high-intensity laser–solid interactions

Matter and Radiation at Extremes
We investigate the dynamics of convergent shock compression in solid cylindrical targets irradiated by an ultrafast relativistic laser pulse. Our particle-in-cell simulations and coupled hydrodynamic simulations reveal that the compression process is ...
Long Yang, Martin Rehwald, Thomas Kluge, Alejandro Laso Garcia, Toma Toncian, Karl Zeil, Ulrich Schramm, Thomas E. Cowan, Lingen Huang   +8 more
doaj   +1 more source

Compression of dynamic tactile information in the human hand

Science Advances, 2020
The mechanics of wave transmission in the human hand effect the preneuronal compression of tactile information. A key problem in the study of the senses is to describe how sense organs extract perceptual information from the physics of the environment ...
Yitian Shao, V. Hayward, Y. Visell
semanticscholar   +1 more source