Results 61 to 70 of about 1,600,748 (340)

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Conceptual design of heavy ion beam compression using a wedge

Physical Review Special Topics. Accelerators and Beams, 2015
Heavy ion beams are a useful tool for conducting high energy density physics (HEDP) experiments. Target heating can be enhanced by beam compression, because a shorter pulse diminishes hydrodynamic expansion during irradiation.
Jonathan C. Wong, B. Grant Logan, Simon S. Yu   +2 more
doaj   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

A compressible multifluid system with new physical relaxation terms [PDF]

Annales scientifiques de l'École normale supérieure, 2019
In this paper, we rigorously derive a new compressible multifluid system from compressible Navier-Stokes equations with density-dependent viscosity in the one-dimensional in space setting. More precisely, we propose and mathematically derive a generalization of the usual one velocity Baer-Nunziato model with a new relaxation term in the PDE governing ...
Bresch, Didier, Hillairet, Matthieu
openaire   +5 more sources

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

A New Fourth Order Compression Dependent Equation of State

East European Journal of Physics
This study introduces a new first- to fourth-order exponential equation of state (EOS) to enhance accuracy across varying compression levels. The proposed exponential EOS is compared to the widely used fourth-order Birch-Murnaghan EOS, and it not only ...
Abhay P. Srivastava, Brijesh K. Pandey, Anod Kumar Singh, Reetesh Srivastava   +3 more
doaj   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

High strain rate tensile and compressive effects in glassy polymers

EPJ Web of Conferences, 2012
Polymers are increasingly used in impact and complex high rate loading applications. Generally, the mechanical response of glassy polymers under high strain rates has been determined in compression.
Woodworth B.T., Siviour C.R., Jordan J.L.   +2 more
doaj   +1 more source

Review of Multi-Physics Modeling on the Active Magnetic Regenerative Refrigeration

Mathematical and Computational Applications, 2021
Compared to conventional vapor-compression refrigeration systems, magnetic refrigeration is a promising and potential alternative technology. The magnetocaloric effect (MCE) is used to produce heat and cold sources through a magnetocaloric material (MCM).
Julien Eustache, Antony Plait, Frédéric Dubas, Raynal Glises   +3 more
doaj   +1 more source