Results 1 to 10 of about 128,864 (318)

Biomarkers and clinical predictors of long-term course in obsessivecompulsive disorder: A prospective cohort study

open access: yesEuropean Psychiatry, 2023
Introduction The purpose of the research project is to analyze the long-term evolution of obsessive-compulsive disorder (OCD) from of a study of a cohort of patients prospectively followed over a period ranging from 5 to 20 years, treated for according ...
S. López-Rodriguez   +7 more
doaj   +1 more source

Sexually dimorphic role for insular perineuronal nets in aversion-resistant alcohol consumption

open access: yesFrontiers in Psychiatry, 2023
Compulsive alcohol drinking is a key symptom of alcohol use disorder (AUD) that is particularly resistant to treatment. An understanding of the biological factors that underly compulsive drinking will allow for the development of new therapeutic targets ...
Luana Martins de Carvalho   +3 more
doaj   +1 more source

The SEEKING Drive and Its Fixation: A Neuro-Psycho-Evolutionary Approach to the Pathology of Addiction

open access: yesFrontiers in Human Neuroscience, 2021
Neuro-ethological studies conducted by Panksepp and his colleagues have provided an understanding of how the activity of the mesolimbic dopaminergic (ML DA) system leads to the emotional disposition to SEEK/Explore, which is involved in all appetitive ...
Antonio Alcaro   +2 more
doaj   +1 more source

Writing Abilities in Compulsive Prisoners

open access: yesFrontiers in Psychology, 2021
Research has found links between academic failure and criminal offending and suggest that many incarcerated young people have experienced significant behavioral and learning problems in school, which could result in criminal outcomes and poor academic ...
Lucas Muñoz-López   +5 more
doaj   +1 more source

Compulsivity in obsessive–compulsive disorder and addictions [PDF]

open access: yesEuropean Neuropsychopharmacology, 2016
Compulsive behaviors are driven by repetitive urges and typically involve the experience of limited voluntary control over these urges, a diminished ability to delay or inhibit these behaviors, and a tendency to perform repetitive acts in a habitual or stereotyped manner.
Figee, Martijn   +8 more
openaire   +6 more sources

Viral-Mediated Knockdown of Nucleus Accumbens Shell PAC1 Receptor Promotes Excessive Alcohol Drinking in Alcohol-Preferring Rats

open access: yesFrontiers in Behavioral Neuroscience, 2021
Alcohol use disorder (AUD) is a chronic, relapsing disorder whose genetic and environmental susceptibility components are not fully understood. Neuropeptidergic signaling has been repeatedly implicated in modulating excessive alcohol drinking, especially
Margaret A. Minnig   +4 more
doaj   +1 more source

Ahead of the Curve: Responses From Patients in Treatment for Obsessive-Compulsive Disorder to Coronavirus Disease 2019

open access: yesFrontiers in Psychology, 2020
Alongside concern about the physical health impacts of the coronavirus disease 2019 (COVID-19) crisis, public health officials have also raised concerns about the potential for massive mental health impact.
Jennie M. Kuckertz   +13 more
doaj   +1 more source

A new approach to assess gambling-like behavior in laboratory rats: using intracranial self-stimulation as a positive reinforcer

open access: yesFrontiers in Behavioral Neuroscience, 2014
Pathological gambling is one manifestation of impulse control disorders. The biological underpinnings of these disorders remain elusive and treatment is far from ideal.
Stephanie E Tedford   +8 more
doaj   +1 more source

Short communication: A report of the first twelve months of an early intervention service for obsessive-compulsive disorder (OCD)

open access: yesComprehensive Psychiatry, 2021
Objectives: To present a report on the first twelve months of an early intervention service for patients with obsessive-compulsive and related disorders.
Vlasios Brakoulias   +2 more
doaj   +1 more source

A longitudinal evaluation of free will related cognitions in obsessive–compulsive disorder

open access: yesBMC Psychiatry, 2022
Background Individuals with obsessive–compulsive disorder (OCD) often feel compelled to perform (compulsive) behaviors, thus raising questions regarding their free will beliefs and experiences.
Maria E. Moreira-de-Oliveira   +5 more
doaj   +1 more source

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