Results 61 to 70 of about 58,348 (262)

Xenophobia in Media: Reconstruction of Subjectivity in Iqbal Al-Qazwini’s Zubaida’s Window

open access: yesCritical Literary Studies
The present study argues the relationship between the media’s power and the reconstruction of subjectivity in Zubaida’s Window, a novel by Iqbal Al-Qazwini.
Mahshid Namjoo   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Assessing the Socio-economic Effects of Reservoir Dam Construction, Case Study; Siahzakh in Divandareh, Iran [PDF]

open access: yesجغرافیا و پایداری محیط, 2017
The socio-economic and environmental consequences of dam construction can be irreversible. The ecosystem of reservoir dams is only examined prior to the construction and the effects of post-construction are not investigated.
Peyman Akbarzadeh   +1 more
doaj  

Actualities in logistics and transport [PDF]

open access: yes
The increasing flow of commodities represents a fundamental component of the actual changes within the economic systems at global, regional and local frameworks.
Liliana Nicodim, Simona Dordea
core  

In the eye of the storm: preliminary evidence on the use of online learning diaries [PDF]

open access: yes, 2009
The surprising lack of pressure and speed in the centre of the vortex of a storm are in stark contrast to the force and destruction often experienced at its periphery.
Galpin, Fenella   +2 more
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Healthcare financing in OECD countries beyond the public-private split [PDF]

open access: yes
Background: Studies of long-term trends in the healthcare financing mix generally focus on a dichotomous concept discerning public from private funding sources. More detailed analyses of the funding mix tend to be restricted to a small number of cases or
Götze, Ralf, Schmid, Achim
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

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