Results 121 to 130 of about 30,213 (286)

A Creative Nondeterministic Computability

open access: yesRUDN Journal of Philosophy, 2009
This paper shows a range of fundamental limitations inherent to any process realized in a standard theory of deterministic computability that significantly hamper its application to an analysis of philosophical problems concerning time-flow phenomena ...
A M Anisov
doaj  

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

How to approximate fuzzy sets: mind-changes and the Ershov Hierarchy. [PDF]

open access: yesSynthese, 2023
Bazhenov N   +3 more
europepmc   +1 more source

To Compute or Not Compute

open access: yes, 1979
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +2 more sources

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Optical Computing and Computational Complexity

open access: yes, 2006
This work concerns the computational complexity of a model of computation that is inspired by optical computers. The model is called the continuous space machine and operates in discrete timesteps over a number of two-dimensional images of fixed size and arbitrary spatial resolution.
openaire   +2 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Shifts with Decidable Language and Non-Computable Entropy

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2008
We consider subshifts of the full shift of all binary bi-infinite sequences. On the one hand, the topological entropy of any subshift with computably co-enumerable language is a right-computable real number between 0 and 1.
Peter Hertling, Christoph Spandl
doaj  

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

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