Results 91 to 100 of about 120,189 (290)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Computability and Complexity in Analysis.

J. Univers. Comput. Sci., 2008
Computability and Complexity in ...
Brattka,Vasco, Ishihara,Hajime, Schröder,Matthias, Zhong,Ning   +3 more
openaire   +3 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Analysis of an age-dependent SI epidemic model with disease-induced mortality and proportionate mixing assumption: the case of vertically transmitted diseases

Journal of Applied Mathematics, 2004
An SI epidemic model for a vertically as well as horizontally transmitted disease is investigated when the fertility, natural mortality, and disease-induced mortality rates depend on age and the force of infection corresponds to a special form of ...
M. El-Doma
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

NON-KEYNESIAN EFFECTS OF FISCAL DISCIPLINE: A COMPUTABLE GENERAL EQUILIBRIUM ANALYSIS FOR TURKEY

Sosyal Ekonomik Araştırmalar Dergisi, 2005
Bu makalenin amacı en son hazırlanan verileri kullanarak, analitik bir araç olan hesaplanabilir denge model yöntemi ile, Türkiye için dinamik bir model dizayn etmektir.
Murat ASLAN
doaj   +4 more sources

Electronic Commerce and Developing Countries: a Computable General Equilibrium Analysis

Economía, 2002
Es ampliamente reconocido que el comercio electrónico reduce costos de transacción, incrementa la eficiencia y produce importantes cambios en la administración y los procesos productivos de los negocios.
Juan Pizarro Ríos
doaj  

Functional a posteriori error estimates for time-periodic parabolic optimal control problems

, 2015
This paper is devoted to the a posteriori error analysis of multiharmonic finite element approximations to distributed optimal control problems with time-periodic state equations of parabolic type.
Langer, Ulrich, Repin, Sergey, Wolfmayr, Monika   +2 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Una revisión de los efectos del Tratado de Libre Comercio entre Colombia y Estados Unidos

Lecturas de Economía, 2014
Una revisión de los efectos del Tratado de Libre Comercio entre Colombia y Estados Unidos Resumen: En la evaluación de políticas arancelarias se han utilizado ampliamente los modelos de equilibrio general computable como herramienta para el análisis y ...
Gustavo Hernández
doaj   +1 more source