Results 71 to 80 of about 10,740 (264)

Organizational analysis in computer science [PDF]

open access: yesThe Information Society, 1993
Computer science in the United States is hard pressed to show broad utility to help justify billion dollar research programs and the value of educating well over 40,000 bachelor of science and mast...
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Quantum Doeblin Coefficients: Interpretations and Applications [PDF]

open access: yesQuantum
In classical information theory, the Doeblin coefficient of a classical channel provides an efficiently computable upper bound on the total-variation contraction coefficient of the channel, leading to what is known as a strong data-processing inequality.
Ian George   +3 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Computation-Based Reliability Analysis [PDF]

open access: yesIEEE Transactions on Computers, 1976
A reliability analysis method for computing systems is considered in which the underlying criteria for "success" are based on the computations the system must perform in the use environment. Beginning with a general model of a "computer with faults," intermediate concepts of a "tolerance relation" and an "environment space" are introduced which account
openaire   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

NON-KEYNESIAN EFFECTS OF FISCAL DISCIPLINE: A COMPUTABLE GENERAL EQUILIBRIUM ANALYSIS FOR TURKEY

open access: yesSosyal Ekonomik Araştırmalar Dergisi, 2005
Bu makalenin amacı en son hazırlanan verileri kullanarak, analitik bir araç olan hesaplanabilir denge model yöntemi ile, Türkiye için dinamik bir model dizayn etmektir.
Murat Aslan
doaj   +4 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Analysis of an age-dependent SI epidemic model with disease-induced mortality and proportionate mixing assumption: the case of vertically transmitted diseases

open access: yesJournal of Applied Mathematics, 2004
An SI epidemic model for a vertically as well as horizontally transmitted disease is investigated when the fertility, natural mortality, and disease-induced mortality rates depend on age and the force of infection corresponds to a special form of ...
M. El-Doma
doaj   +1 more source

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