Results 71 to 80 of about 120,189 (290)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Sketching a "low-cost" text-classification technique for text topics in English [PDF]
Ibérica, 2014 The aim of this paper is to sketch a potential methodology for automatic text classification which allows text topic discrimination as a prior step to new case assignment to previously established text topics.
Pascual Cantos Gómez
doaj +1 more source
Computable analysis for verified exact real computation [PDF]
, 2020 We use ideas from computable analysis to formalize exact real number computation in the Coq proof assistant. Our formalization is built on top of the Incone library, a Coq library for computable analysis. We use the theoretical framework that computable analysis provides to systematically generate target specifications for real number algorithms. First
Konečný, Michal +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Measuring Sustainable Development: The Use of Computable General Equilibrium Models [PDF]
This paper advocates computable general equilibrium models as a methodological tool that is particularly suitable for measuring the impacts of policy interference on the three dimensions of sustainable development, i.e.
Böhringer, Christoph, Löschel, Andreas
core
The demographic challenge facing Scottish HEIs: a computable general equilibrium analysis [PDF]
, 2009 This paper measures the regional demand impacts on output and employment of Scottish Higher Education Institutions (HEIs) based on Input-Output tables for the year 2006.
Hermannsson, K. +3 more
core
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Organizational analysis in computer science [PDF]
The Information Society, 1993 Computer science in the United States is hard pressed to show broad utility to help justify billion dollar research programs and the value of educating well over 40,000 bachelor of science and mast...
openaire +2 more sources