Results 141 to 150 of about 3,148,089 (334)

Neuro-Logocentric Representation of Brain Activity as a Conceptual Basis for Artificial Neural Networks: a Critical Analysis

open access: yesГалактика медиа: журнал медиа исследований
The aim of this article is a critical analysis of the logocentric representation of brain as a conceptual basis for artificial neural networks (ANNs).
Anton I. Zhelnin
doaj   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

A new mathematical model to improve encryption process based on Split-Radix Fast Fourier Transform algorithm

open access: yesFrontiers in Computer Science
This paper introduces a new encryption method aimed at improving the cryptography process through the use of splitting radix Fourier Transform technique called Split-Radix Fast Fourier Transforms (SRFFT). The proposed method is based on splitting the FFT
Abdulle Hassan Mohamud
doaj   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Assessing the Regulatory Impact of the Turkish Competition Authority on Market Dynamics: A Statistical Approach Using Kernel Estimation and its Simulation

open access: yesMehmet Akif Ersoy Üniversitesi İktisadi ve İdari Bilimler Fakültesi Dergisi
Established in Turkey in 1994, the Competition Authority plays a key role in safeguarding and promoting competition in markets. Its main tasks include monitoring agreements, detecting collusive practices and preventing the formation of cartels, as well ...
Murat Aydın, Mehmet Niyazi Çankaya
doaj   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Clinical Ethics – To Compute, or Not to Compute?

open access: yesThe American Journal of Bioethics, 2022
Meier, Lukas J   +3 more
openaire   +3 more sources

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