Results 1 to 10 of about 203,667 (165)

Computational Biology and Bioinformatics in Nigeria [PDF]

open access: yesPLoS Computational Biology, 2014
Over the past few decades, major advances in the field of molecular biology, coupled with advances in genomic technologies, have led to an explosive growth in the biological data generated by the scientific community. The critical need to process and analyze such a deluge of data and turn it into useful knowledge has caused bioinformatics to gain ...
Marion Adebiyi   +2 more
exaly   +8 more sources

Bioinformatics and Computational Biology in Poland

open access: yesPLoS Computational Biology, 2013
The series of articles in PLOS Computational Biology on the development of bioinformatics activities in various countries, e.g., China [1], Australia [2], and Singapore [3], and the formation and successful development of the Polish Bioinformatics Society over the last five years, have inspired us to present a personal perspective on the advances of ...
Jerzy Tiuryn, Janusz Bujnicki
exaly   +5 more sources

Chromatin information content landscapes inform transcription factor and DNA interactions

open access: yesNature Communications, 2021
Interaction between transcription factors and chromatin is fundamental for genome organization and regulation. Here, the authors use information theory to measure signatures of organized chromatin resulting from transcription factor-chromatin ...
Ricardo D’Oliveira Albanus   +6 more
doaj   +1 more source

Molecular Computing and Bioinformatics [PDF]

open access: yesMolecules, 2019
Molecular computing and bioinformatics are two important interdisciplinary sciences that study molecules and computers. Molecular computing is a branch of computing that uses DNA, biochemistry, and molecular biology hardware, instead of traditional silicon-based computer technologies.
Xin Liang, Wen Zhu, Zhibin Lv, Quan Zou
openaire   +3 more sources

Genetic determination of regional connectivity in modelling the spread of COVID-19 outbreak for more efficient mitigation strategies

open access: yesScientific Reports, 2023
For the COVID-19 pandemic, viral transmission has been documented in many historical and geographical contexts. Nevertheless, few studies have explicitly modeled the spatiotemporal flow based on genetic sequences, to develop mitigation strategies ...
Leonidas Salichos   +4 more
doaj   +1 more source

Improving fragment-based ab initio protein structure assembly using low-accuracy contact-map predictions

open access: yesNature Communications, 2021
Predicting protein structure from sequence is still not possible for all proteins. Here, the authors introduce a method that integrates deep learning and information about protein co-evolution to guide the prediction of non-homologous protein structures ...
S. M. Mortuza   +5 more
doaj   +1 more source

Deep learning and transfer learning identify breast cancer survival subtypes from single-cell imaging data

open access: yesCommunications Medicine, 2023
Background Single-cell multiplex imaging data have provided new insights into disease subtypes and prognoses recently. However, quantitative models that explicitly capture single-cell resolution cell-cell interaction features to predict patient survival ...
Shashank Yadav   +4 more
doaj   +1 more source

A retrospective descriptive study of cranioplasty failure rates and contributing factors in novel 3D printed calcium phosphate implants compared to traditional materials

open access: yes3D Printing in Medicine, 2020
Background Failure rates with cranioplasty procedures have driven efforts to improve graft material and reduce reoperation. One promising allograft source is a 3D-printed titanium mesh with calcium phosphate filler. This study evaluated failure rates and
Michael Koller   +5 more
doaj   +1 more source

Cloud Computing in Bioinformatics [PDF]

open access: yes, 2010
Cloud Computing presents a new approach to allow the development of dynamic, distributed and highly scalable software. For this purpose, Cloud Computing offers services, software and computing infrastructure independently through the network. To achieve a system that supports these characteristics, Service-Oriented Architectures (SOA) and agent ...
Javier Bajo   +4 more
openaire   +3 more sources

Vessel segmentation for X-ray coronary angiography using ensemble methods with deep learning and filter-based features

open access: yesBMC Medical Imaging, 2022
Background Automated segmentation of coronary arteries is a crucial step for computer-aided coronary artery disease (CAD) diagnosis and treatment planning.
Zijun Gao   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy