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Bioinformatics and the Internet are the linked themes of this year's special issue on computers. They are two of computer science's boom areas, where growth and growing pains are both extraordinary.
Tim Appenzeller, Gilbert Chin
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Computational cell biology [PDF]
![Graphic][1] ©The New Yorker Collection from cartoonbank.com. All rights reserved. All of us who do experiments and think about biology on a daily basis know that biological systems are exceedingly complex.
Ira Mellman, Tom Misteli
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Computational Systems Biology [PDF]
The complex biological systems consist of distinct molecules that exert their functions by interacting with each other, which makes it a big challenge to understand how the cellular machinery works. Recently, the accumulation of a large amount of multiscale omics data, such as next-generation sequencing data and protein interaction data, provides ...
Weidong Tian+3 more
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Cancer computational biology [PDF]
EditorialIntroduction of high-throughput measurement technolo-gies combined with the increase of the scientific knowl-edge base, with respect to our understanding of cellularand biological processes, resulted in establishing compu-ter and information science as an important and funda-mental component of modern biology.
Zohar Yakhini+3 more
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Correction: Assessment of ab initio models of protein complexes by molecular dynamics. [PDF]
[This corrects the article DOI: 10.1371/journal.pcbi.1006182.].
PLOS Computational Biology Staff
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Quantum Computing for Molecular Biology** [PDF]
AbstractMolecular biology and biochemistry interpret microscopic processes in the living world in terms of molecular structures and their interactions, which are quantum mechanical by their very nature. Whereas the theoretical foundations of these interactions are well established, the computational solution of the relevant quantum mechanical equations
Alberto Baiardi+2 more
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Correction: Limits on reliable information flows through stochastic populations. [PDF]
[This corrects the article DOI: 10.1371/journal.pcbi.1006195.].
PLOS Computational Biology Staff
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Computational biology for ageing [PDF]
High-throughput genomic and proteomic technologies have generated a wealth of publicly available data on ageing. Easy access to these data, and their computational analysis, is of great importance in order to pinpoint the causes and effects of ageing.
Matthias Ziehm+3 more
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Correction: Lack of Ecological and Life History Context Can Create the Illusion of Social Interactions in Dictyostelium discoideum. [PDF]
[This corrects the article DOI: 10.1371/journal.pcbi.1005246.].
PLOS Computational Biology Staff
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