Results 41 to 50 of about 502,236 (314)
Computational and Systems Biology [PDF]
M. Madan Babu and Hirotada Mori introduce this themed issue of Molecular BioSystems focusing on Computational and systems biology
M Madan, Babu, Hirotada, Mori
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Correction: The role of the encapsulated cargo in microcompartment assembly. [PDF]
[This corrects the article DOI: 10.1371/journal.pcbi.1006351.].
PLOS Computational Biology Staff
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Our understanding of biology has undergone a revolution in the past 20 years, driven by our ability to capture, store, interrogate and analyze the ever-increasing volumes of ‘omics’ data.
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Synthetic biology—putting engineering into biology [PDF]
Synthetic biology is interpreted as the engineering-driven building of increasingly complex biological entities for novel applications. Encouraged by progress in the design of artificial gene networks, de novo DNA synthesis and protein engineering, we ...
Panke, Sven +3 more
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Marrying computers with biology [PDF]
An interesting symposium last month suggests that computation and molecular biology, already interdependent, are about to become inextricably linked.
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[This corrects the article DOI: 10.1371/journal.pcbi.1007804.].
PLOS Computational Biology Staff
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The computational stance in biology [PDF]
The goal of this article is to call attention to, and to express caution about, the extensive use of computation as an explanatory concept in contemporary biology. Inspired by Dennett's ‘intentional stance’ in the philosophy of mind, I suggest that a ‘computational stance’ can be a productive approach to evaluating the value of computational concepts ...
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Correction: A Computational Framework for 3D Mechanical Modeling of Plant Morphogenesis with Cellular Resolution. [PDF]
[This corrects the article DOI: 10.1371/journal.pcbi.1003950.].
PLOS Computational Biology Staff
doaj +1 more source
A Molecular Biology Database Digest [PDF]
Computational Biology or Bioinformatics has been defined as the application of mathematical and Computer Science methods to solving problems in Molecular Biology that require large scale data, computation, and analysis [18].
Kröger, Peer +3 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source

