Results 61 to 70 of about 993,851 (283)

Software that goes with the flow in systems biology [PDF]

, 2010
A recent article in BMC Bioinformatics describes new advances in workflow systems for computational modeling in systems biology. Such systems can accelerate, and improve the consistency of, modeling through automation not only at the simulation and ...
A Funahashi, C Li, D Köhn, F Krause, J Schaff, M Hucka, M Kanehisa, Michael Hucka, MJ Herrgård, N Le Novère, Nicolas Le Novère, P Li, S Hoops, T Forth, U Wittig   +14 more
core   +3 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Correction: lumpGEM: Systematic generation of subnetworks and elementally balanced lumped reactions for the biosynthesis of target metabolites. [PDF]

PLoS Computational Biology, 2017
[This corrects the article DOI: 10.1371/journal.pcbi.1005513.].
PLOS Computational Biology Staff
doaj   +1 more source

Book of abstracts: Scientific Opening of The Microsoft Reasearch Centre for Computational and Systems Biology, Trento, Italy, April 3-5, 2006 [PDF]

, 2006
s of the talks of the Scientific Opening of the Microsoft Research - University of Trento Centre for Computational and Systems Biology held in Trento on April 3-5 ...
Baralla, Angela, Cappello, Igor, Cavaliere, Matteo, Csikasz-Nagy, Attila, Hillston, Jane, Montanari, Ugo, Mura, Ivan, Priami, Corrado, Walker, David   +8 more
core  

Computational biology: plus c'est la même chose, plus ça change [PDF]

, 2013
A report on the joint 19th Annual International Conference on Intelligent Systems for Molecular Biology (ISMB)/10th Annual European Conference on Computational Biology (ECCB) meetings and the 7th International Society for Computational Biology Student ...
Huttenhower, Curtis
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Erratum: Notification of Republication: Modeling individual time courses of thrombopoiesis during multi-cyclic chemotherapy. [PDF]

PLoS Computational Biology, 2019
[This corrects the article DOI: 10.1371/journal.pcbi.1006775.].
PLOS Computational Biology Staff
doaj   +1 more source

Chaste: an open source C++ library for computational physiology and biology [PDF]

, 2013
Chaste - Cancer, Heart And Soft Tissue Environment - is an open source C++ library for the computational simulation of mathematical models developed for physiology and biology.
A Cedilnik, A Corrias, A Garny, A Prlić, AC Hindmarsh, AG Fletcher, Alberto Corrias, Alexander G. Fletcher, Andreas Prlic, C Bradley, C Crosnier, C Lopez-Garcia, CH Luo, Christopher J. Arthurs, CJ Arthurs, D Waltemath, D Waltemath, Daniel G. Harvey, David J. Gavaghan, E Pueyo, F Graner, G Karypis, G Wilson, Gary R. Mirams, GR Christie, GR Mirams, GR Mirams, GR Mirams, GR Mirams, GT Eisenhoffer, H Honda, H Perfahl, HJ Snippert, IMM van Leeuwen, J Cooper, J Cooper, J Cooper, J Moreira, J Pitt-Francis, J Southern, J Walmsley, James M. Osborne, James Southern, JM Osborne, Joe Pitt-Francis, Jonathan Cooper, JR Collier, K Beck, K Gima, KM Sanders, M Bernabeu, M Hucka, M Weliky, Megan E. Marsh, Miguel O. Bernabeu, ML Buist, MO Bernabeu, MO Bernabeu, MO Bernabeu, N Le Nov'ere, N Zemzemi, Nejib Zemzemi, P Macklin, P Pathmanathan, P Pathmanathan, P Pathmanathan, P Pathmanathan, P Pathmanathan, Pras Pathmanathan, R Bordas, Rafel Bordas, SA Niederer, Sara-Jane Dunn, SJ Dunn, SJ Dunn, SM Baxter, T Cickovski, Yohan Davit, Z Merali, Z Qu   +79 more
core   +5 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Computational Biology

International Journal of Advanced Research in Computer Science and Software Engineering, 2018
In the last 20 years, biological sequence data have been accumulating at exponential rate under continuous improvement of sequencing technology, progress in computer science, and steady increase of funding. Molecular sequence databases (e.g., EMBL, Genbank, DDJB, Entrez, Swissprot, etc.) currently collect hundreds of thousands of sequences of ...
Dagmar Klostermeier, Markus G. Rudolph
  +5 more sources