Correction: Complex Dynamics of Virus Spread from Low Infection Multiplicities: Implications for the Spread of Oncolytic Viruses. [PDF]
PLoS Computational Biology, 2017 [This corrects the article DOI: 10.1371/journal.pcbi.1005241.].
PLOS Computational Biology Staff
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Converting Life into Numbers [PDF]
, 2014 Biological data exists in several layers from genome sequence to networks and beyond. Information that comes from environment passes through layers of viscosity within organisms and is transformed into an output released back into the environment.
Dhar, Pawan K; Centre for Systems and Synthetic Biology, Department of Computational Biology and Bioinformatics, University of Kerala, Trivandrum, Kerala
core
Pedagogical Transformation of Biology Teacher Candidates: Integration of Computational Thinking into STEM Learning [PDF]
This study analyzed the effectiveness of integrating Computational Thinking (CT)-based STEM learning in prospective biology teachers at PGRI Pontianak University, exploring students' perceptions, attitudes, challenges, and opportunities. This integration
Herditiya, Herditiya, Nawawi, Nawawi
core +1 more source
In-silico design of an Epitope-based peptide vaccine: A Computational Biology Approach [PDF]
, 2016 Lymphocytic choriomeningitis, is a rodent-borne viral infectious disease caused by Lymphocytic choriomeningitis virus (LCMV), a member of the family Arenaviridae, that was initially isolated in 1933.
Sahrawat, Tammanna Ravee; Centre for Systems Biology and Bioinformatics, UIEAST, Panjab University, Chandigarh
core
The computational stance in biology [PDF]
Philosophical Transactions of the Royal Society B: Biological Sciences, 2019 The goal of this article is to call attention to, and to express caution about, the extensive use of computation as an explanatory concept in contemporary biology. Inspired by Dennett's ‘intentional stance’ in the philosophy of mind, I suggest that a ‘computational stance’ can be a productive approach to evaluating the value of computational concepts ...
openaire +2 more sources
When kinases meet mathematics: the systems biology of MAPK signalling [PDF]
, 2005 The mitogen activated protein kinase/extracellular signal regulated kinase pathway regulates fundamental cellular function such as cell proliferation, survival, differentiation and motility, raising the question how these diverse functions are specified ...
Calder, M. +5 more
core +1 more source
Computational Biology in Brazil
PLoS Computational Biology, 2007 At the request of the PLoS Computational Biology Editor-in-Chief, I agreed to write about computational biology in Brazil (see author information in Box 1). That meant describing: a) the history of the field in our country (short as the history of the field itself is short); b) the current state of the field in Brazil; c) the influence of computational
openaire +5 more sources
Computational Biology Approach for Therapeutic Intervention of Alexander Disease by Post Transcriptional Gene Silencing [PDF]
, 2017 Alexander disease (AxD) primarily affects the white matter of the central nervous system (CNS). It is an astrogliopathy in which Astroglial cells involved in maintenance homeostasis and providing defence to the brain are affected.
Sahrawat, Tammanna Ravee; Centre for Systems Biology and Bioinformatics, UIEAST, Panjab University, Chandigarh
core
Correction: Comprehensive Sieve Analysis of Breakthrough HIV-1 Sequences in the RV144 Vaccine Efficacy Trial. [PDF]
PLoS Computational Biology, 2016 [This corrects the article DOI: 10.1371/journal.pcbi.1003973.].
PLOS Computational Biology Staff
doaj +1 more source