Results 51 to 60 of about 3,347,103 (312)
A Molecular Biology Database Digest [PDF]
, 2000 Computational Biology or Bioinformatics has been defined as the application of mathematical and Computer Science methods to solving problems in Molecular Biology that require large scale data, computation, and analysis [18].
Kröger, Peer +3 more
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PLoS Computational Biology, 2021 [This corrects the article DOI: 10.1371/journal.pcbi.1007804.].
PLOS Computational Biology Staff
doaj +1 more source
, 2019 Our understanding of biology has undergone a revolution in the past 20 years, driven by our ability to capture, store, interrogate and analyze the ever-increasing volumes of ‘omics’ data.
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Synthetic biology—putting engineering into biology [PDF]
, 2006 Synthetic biology is interpreted as the engineering-driven building of increasingly complex biological entities for novel applications. Encouraged by progress in the design of artificial gene networks, de novo DNA synthesis and protein engineering, we ...
Panke, Sven +3 more
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Towards molecular systems biology of gene transcription and regulation [PDF]
, 2010 Ten years after the determination of the RNA polymerase 11 structure, the basic mechanism of mRNA synthesis during gene transcription is known. In the future, the initiation and regulation of transcription must be studied with a combination of structural
Cramer, P., Cramer, Patrick
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Correction: A Computational Framework for 3D Mechanical Modeling of Plant Morphogenesis with Cellular Resolution. [PDF]
PLoS Computational Biology, 2016 [This corrects the article DOI: 10.1371/journal.pcbi.1003950.].
PLOS Computational Biology Staff
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Guest Editorial: Computational Biology [PDF]
, 2014 Computational biology has been used to help sequence the human genome, create accurate models of the human brain, and assist in modeling biological systems. With the availability of massive datasets, it has also become possible to study different systems
Gupta, Pushpendra K; Ch. Charan Singh University Meerut, UP India
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Computational Biology and Bioinformatics in Nigeria [PDF]
PLoS Computational Biology, 2014 Over the past few decades, major advances in the field of molecular biology, coupled with advances in genomic technologies, have led to an explosive growth in the biological data generated by the scientific community. The critical need to process and analyze such a deluge of data and turn it into useful knowledge has caused bioinformatics to gain ...
Adoga, Moses +10 more
openaire +7 more sources