Results 71 to 80 of about 4,213,444 (308)
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Limits of computational biology
In Silico Biology, 2015 Abstract Are we close to a complete inventory of living processes so that we might expect in the near future to reproduce every essential aspect necessary for life? Or are there mechanisms and processes in cells and organisms that are presently inaccessible to us?
openaire +3 more sources
Computational systems biology: integration of sequence, structure, network, and dynamics [PDF]
, 2011 A report of the 4nd International Conference on Computational Systems Biology, 9-11 September 2010, Suzhou, China.
Xiang-Sun Zhang, Yong Wang, Luonan Chen
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PLoS Computational Biology[This corrects the article DOI: 10.1371/journal.pcbi.1013876.].
PLOS Computational Biology Staff
doaj +1 more source
PLoS Computational Biology, 2023 [This corrects the article DOI: 10.1371/journal.pcbi.1010383.].
PLOS Computational Biology Staff
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FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Computer Algebra in Systems Biology [PDF]
American Mathematical Monthly, 2009 Systems biology focuses on the study of entire biological systems rather than on their individual components. With the emergence of high-throughput data generation technologies for molecular biology and the development of advanced mathematical modeling techniques, this field promises to provide important new insights.
Reinhard C. Laubenbacher +1 more
openaire +4 more sources
A Molecular Biology Database Digest [PDF]
, 2000 Computational Biology or Bioinformatics has been defined as the application of mathematical and Computer Science methods to solving problems in Molecular Biology that require large scale data, computation, and analysis [18].
Kröger, Peer +3 more
core +1 more source
Correction: Infectious reactivation of cytomegalovirus explaining age- and sex-specific patterns of seroprevalence. [PDF]
PLoS Computational Biology, 2019 [This corrects the article DOI: 10.1371/journal.pcbi.1005719.].
PLOS Computational Biology Staff
doaj +1 more source