Results 1 to 10 of about 2,147,957 (198)

Peptide-Based Therapeutics for Alzheimer's Disease: Medicinal Chemistry, AI-Guided Computational Design, and Blood-Brain Barrier Delivery. [PDF]

Drug Des Devel Ther
Al Khzem AH, Gomaa MS.
europepmc   +1 more source

Computational Design of Broad-Spectrum Ebola Antibodies through Framework and Complementarity-Determining Region Synergistic Optimization. [PDF]

Research (Wash D C)
Zhang X, Liu X, Zhou J, Gao P, Pan S, Yang X, Duan H, Liao Y, Zhang F, Dong X, Liu J, Chi X, Yang W.   +12 more
europepmc   +1 more source

A Novel Multi-Tiered Hybrid Virtual Screening Pipeline for the Discovery of WDR5-MLL1 Interaction Disruptors in Precision Cancer Therapy

ACS Omega
Anwar Abuelrub, Ismail Erol, Serdar Durdağı   +2 more
doaj   +1 more source

Computational design of a novel multi-epitope vaccine candidate against group A rotavirus. [PDF]

Virol J
Pajand O, Larimi AG, Ahmad S, Mahooti M, Mohammadi G, Sanami S.   +5 more
europepmc   +1 more source

Computational design of bifaceted protein nanomaterials. [PDF]

Nat Mater
Rankovic S, Carr KD, Decarreau J, Skotheim R, Kibler RD, Ols S, Lee S, Chun JH, Tooley MR, Dauparas J, Eisenach HE, Glögl M, Weidle C, Borst AJ, Baker D, King NP.   +15 more
europepmc   +1 more source

Redefining Therapies for Drug-Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design. [PDF]

Adv Healthc Mater
Carnero Canales CS, Marquez Cazorla JI, Marquez Cazorla RM, Santos AMD, Lobato Duarte J, Oliveira Catarin Nunes L, Reis TC, Cerazi Salvador L, Santos-Filho NA, Sábio RM, Santos HA, Pavan FR.   +11 more
europepmc   +1 more source

Computational Design and Glycoengineering of Interferon-Lambda for Nasal Prophylaxis Against Respiratory Viruses. [PDF]

Adv Sci (Weinh)
Yun J, Yang S, Kwon JH, Vecchietti LF, Choi JH, Choi MR, Ku KB, Ro HJ, Kim KD, Cha M, Chung HJ, Oh JE, Kim HM.   +12 more
europepmc   +1 more source

Targeted computational design of an interleukin-7 superkine with enhanced folding efficiency and immunotherapeutic efficacy. [PDF]

Elife
Lim SK, Lin WC, Pan YC, Huang SW, Yu YA, Chang CH, Hu CJ, Mou CY, Mou KY.   +8 more
europepmc   +1 more source

Computational design of sequence-specific DNA-binding proteins. [PDF]

Nat Struct Mol Biol
Glasscock CJ, Pecoraro RJ, McHugh R, Doyle LA, Chen W, Boivin O, Lonnquist B, Na E, Politanska Y, Haddox HK, Cox D, Norn C, Coventry B, Goreshnik I, Vafeados D, Lee GR, Gordân R, Stoddard BL, DiMaio F, Baker D.   +19 more
europepmc   +1 more source

Clinical Serum-Anchored Computational Design Pipeline for a Broad-Spectrum Influenza Multi-Epitope mRNA Vaccine. [PDF]

Biology (Basel)
Yuan L, Ouyang Z, Zhao Y, Bi R, Wu Y, Li X, Li Y, Song J, Li W, Yan M, Wen S, Luo H, Bai T, Shu Y, Chen Y.   +14 more
europepmc   +1 more source