Results 131 to 140 of about 769,896 (315)

Influences of Ga3+ doping content on microstructure and interfacial polarization in colossal permittivity GayNb0.025Ti0.975-yO2 ceramics

open access: yesInternational Journal of Smart and Nano Materials
Colossal permittivity (CP) materials, particularly co–doped TiO2 ceramics, have garnered significant attention for their potential in high–performance ceramic capacitors.
Wattana Tuichai   +4 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Computational workflow management for conceptual design of complex systems: an air-vehicle design perspective [PDF]

open access: yes, 2007
The decisions taken during the aircraft conceptual design stage are of paramount importance since these commit up to eighty percent of the product life cycle costs. Thus in order to obtain a sound baseline which can then be passed on to the subsequent
Balachandran, Libish Kalathil
core  

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

Formation Embedded Design: a methodology for the integration of fabrication constraints into architectural design [PDF]

open access: yes, 2011
There has been little empirical research on the human aspects of CAD systems. In this paper observations on the analyses of designer activities are presented, by using a systems design approach. The paper concentrates on situation analysis and subsequent
D. Pigram, Pigram, D, W. McGee, McGee, W
core  

Accelerating ab initio melting property calculations with machine learning: application to the high entropy alloy TaVCrW

open access: yesnpj Computational Materials
Melting properties are critical for designing novel materials, especially for discovering high-performance, high-melting refractory materials. Experimental measurements of these properties are extremely challenging due to their high melting temperatures.
Li-Fang Zhu   +5 more
doaj   +1 more source

Computational Design and Optimization of Discrete Shell Structures Made of Equivalent Members

open access: yesBuildings
This paper presents a computational design method for generating discrete shell structures using sets of equivalent discrete members. This study addresses the challenge of reducing the geometrical variety in discrete shell elements by introducing a ...
Arda Ağırbaş, Seçkin Kutucu
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

Refining an understanding of computational thinking [PDF]

open access: yes, 2014
This paper identifies aspects of computational thinking and proposes a description that meets the needs of teachers and academics reflecting upon the developing UK curriculum.
Woollard, John, Selby, Cynthia
core  

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