Results 111 to 120 of about 9,181,016 (294)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Unmanned Helicopter Airborne Fourier Transform Infrared Spectrometer Remote Sensing System for Hazardous Vapors Detection

Applied Sciences
The rapid development of unmanned aerial vehicles (UAVs) provides a new application mode for gas remote sensing. Compared with fixed observation and vehicle-mounted platforms, a Fourier transform infrared spectrometer (FTIR) integrated in the UAV can ...
Zhengyang Shi, Min Huang, Lulu Qian, Wei Han, Guifeng Zhang, Xiangning Lu   +5 more
doaj   +1 more source

Convolutional Deblurring for Natural Imaging

, 2019
In this paper, we propose a novel design of image deblurring in the form of one-shot convolution filtering that can directly convolve with naturally blurred images for restoration.
Hosseini, Mahdi S., Plataniotis, Konstantinos N.   +1 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Deep-learning-enabled temporally super-resolved multiplexed fringe projection profilometry: high-speed kHz 3D imaging with low-speed camera

PhotoniX
Recent advances in imaging sensors and digital light projection technology have facilitated rapid progress in 3D optical sensing, enabling 3D surfaces of complex-shaped objects to be captured with high resolution and accuracy.
Wenwu Chen, Shijie Feng, Wei Yin, Yixuan Li, Jiaming Qian, Qian Chen, Chao Zuo   +6 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Pixel-super-resolved lens-free quantitative phase microscopy with partially coherent illumination

npj Nanophotonics
Lens-free on-chip microscopy (LFOCM) has been widely utilized in digital pathology, drug screening, point-of-care testing (POCT), and quantitative phase imaging (QPI) due to its high throughput imaging capability and compactness.
Yang Chen, Xuejuan Wu, Linpeng Lu, Jiasong Sun, Runnan Zhang, Wenhui Lin, Yufan Chen, Maciej Trusiak, Peng Gao, Chao Zuo   +9 more
doaj   +1 more source

Aberration-corrected differential phase contrast microscopy with annular illuminations

Opto-Electronic Science
Quantitative phase imaging (QPI) enables non-invasive cellular analysis by utilizing cell thickness and refractive index as intrinsic probes, revolutionizing label-free microscopy in cellular research.
Yao Fan, Chenyue Zheng, Yefeng Shu, Qingyang Fu, Lixiang Xiong, Guifeng Lu, Jiasong Sun, Chao Zuo, Qian Chen   +8 more
doaj   +1 more source

Computational medical imaging for total knee arthroplasty using visualitzation toolkit [PDF]

, 2015
This project is presented as a Master Thesis in the field of Civil Engineering, Biomedical specialization. As the project of an Erasmus exchange student, this thesis has been under supervision both the Universite Livre de Bruxelles and the Universitat ...
Romero Sánchez, José Javier
core   +1 more source

On the use of deep learning for computational imaging

Optica, 2019
Since their inception in the 1930–1960s, the research disciplines of computational imaging and machine learning have followed parallel tracks and, during the last two decades, experienced explosive growth drawing on similar progress in mathematical ...
G. Barbastathis, Aydogan Ozcan, G. Situ
semanticscholar   +1 more source