Results 111 to 120 of about 3,599,630 (258)

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

A standardized image processing and data quality platform for rodent fMRI

Nature Communications
Functional magnetic resonance imaging in rodents holds great potential for advancing our understanding of brain networks. Unlike the human community, there remains no standardized resource in rodents for image processing, analysis and quality control ...
Gabriel Desrosiers-Grégoire, Gabriel A. Devenyi, Joanes Grandjean, M. Mallar Chakravarty   +3 more
doaj   +1 more source

Enhanced photoacoustic microscopy with physics-embedded degeneration learning

Opto-Electronic Advances
Deep learning (DL) is making significant inroads into biomedical imaging as it provides novel and powerful ways of accurately and efficiently improving the image quality of photoacoustic microscopy (PAM).
Haigang Ma, Shili Ren, Xiang Wei, Yinshi Yu, Jiaming Qian, Qian Chen, Chao Zuo   +6 more
doaj   +1 more source

Fast Inline Microscopic Computational Imaging. [PDF]

Sensors (Basel), 2022
Ginner L, Breuss S, Traxler L.
europepmc   +1 more source

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran, Malo Gaubert, Alice Dufey, Elise Bannier, Audrey Rico, Jean‐Christophe Ferré, Raphaël Chouteau, Laure Michel, Emmanuelle Le Page, Virginie Callot, Bertrand Audoin, Sarah Demortière, Benoît Combès, Anne Kerbrat   +13 more
wiley   +1 more source

Diffusion equation based parameterization of light field and computational imaging model. [PDF]

Heliyon, 2022
Liu C, Qiu J.
europepmc   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou, Marc Jaskir, Julian Gal, Yombe Fonkeu, Christos Davatzikos, MacLean P. Nasrallah, Jose Garcia, Rubo Xing, Stephen J. Bagley, Arati Desai, Richard E. Phillips, Steven Tobochnik, Colin A. Ellis, James J. Gugger, Nishant Sinha, Joel M. Stein, Kathryn A. Davis   +16 more
wiley   +1 more source

Computational Imaging to Compensate for Soft-Tissue Deformations in Image-Guided Breast Conserving Surgery. [PDF]

IEEE Trans Biomed Eng, 2022
Richey WL, Heiselman JS, Ringel MJ, Meszoely IM, Miga MI.   +4 more
europepmc   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane, Valentina Giunchiglia, Michael C. B. David, Magdalena A. Kolanko, William R. Trender, Peter J. Hellyer, Harmeena Kaur, David J. Sharp, Christopher Carswell, Paresh A. Malhotra, Adam Hampshire   +10 more
wiley   +1 more source

Channeling Fairness: Class Imbalance-Aware Skin Disease Recognition via Fair Channel Enhancement Module

IEEE Access
Skin disease classification presents significant challenges due to class imbalance, low inter-class variability, and high intra-class variation present in most clinical image datasets. To address these issues, we propose Fair Channel Enhancement (FCE), a
Joseph Thomas Ano, Arren Matthew C. Antioquia   +1 more
doaj   +1 more source