Topology‐Aware Deep Learning on Higher‐Order Structures for Drug Response Prediction
We present TopDr, a topology‐aware deep learning framework that encodes both drugs and cell lines as multiscale simplicial complexes, capturing interactions at the 0‐, 1‐, and 2‐simplex levels. By jointly integrating local higher‐order neighborhoods and global topological structures, TopDr generates enriched representations for sensitivity prediction ...
Cong Shen +3 more
wiley +1 more source
Stability analysis of nonlinear algebraic-differential equations with 2-delays and numerical methods. [PDF]
Liao H, Li Q, Xia X, Tang D.
europepmc +1 more source
This review explores the convergence of artificial intelligence technologies in modeling drug–drug and drug–target interactions. By evaluating advanced feature engineering, architectural innovations, and learning paradigms reveals shared evolutionary trends and critical challenges, such as cold‐start settings and shortcut learning.
Xin Sun, Tong Wang
wiley +1 more source
The effect of laser pulse on nonlinear thermoelasticity using an advanced analytical method. [PDF]
Rabie WB +6 more
europepmc +1 more source
PhosSight is a unified deep‐learning framework for phosphoproteome identification, featured by a phosphorylation‐aware detectability predictor. It improves identification sensitivity in DDA through deep re‐localization and rescoring, accelerates DIA searches by detectability‐guided spectral library pruning, and expands phosphoproteome coverage to ...
Ben Wang +10 more
wiley +1 more source
Exact solutions of nonlinear thermodynamic wave patterns in graphene sheets for advanced material applications. [PDF]
Iqbal MAB +5 more
europepmc +1 more source
Photonic‐Enabled Energy‐Efficient Transparent Neuromorphic Computing Devices: A Review
Transparent photonic neuromorphic computing devices merge optics and brain‐inspired computing to overcome von Neumann bottlenecks with ultrafast, low‐energy processing. By exploiting transparent oxides, 2D materials, phase‐change materials, and hybrid heterostructures, these platforms enable photonic synapses, memory, and logic for see‐through edge ...
Shuvaraj Ghosh +8 more
wiley +1 more source
Entropy and thermal dynamics motivated by ternary nanocomposites and geometric influence of oblique channel. [PDF]
Jebali M +7 more
europepmc +1 more source
Giant Bulk Photovoltaic Effect in Two‐Dimensional Topological Ferroelectric Semimetal
ABSTRACT Ferroelectric (FE) metals have attracted growing interest because they combine ferroelectricity with metallic behavior and enable polarization‐controlled band topology near the Fermi level. However, the number of known ferroelectric metals is still limited.
Jianhua Wang +8 more
wiley +1 more source
On using clustering statistics for assessing plasmid binning tools accuracy. [PDF]
Epain V, Mane A, Chauve C.
europepmc +1 more source

