Results 61 to 70 of about 3,490,440 (331)

Documenting research software in engineering science

Scientific Reports, 2022
The reuse of research software needs good documentation, however, the documentation in particular is often criticized. Especially in non-IT specific disciplines, the lack of documentation is attributed to the lack of training, the lack of time or missing
Sibylle Hermann, Jörg Fehr
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Asymptotically consistent and computationally efficient modeling of short-ranged molecular interactions between curved slender fibers undergoing large 3D deformations

Advanced Modeling and Simulation in Engineering Sciences
This article proposes a novel computational modeling approach for short-ranged molecular interactions between curved slender fibers undergoing large 3D deformations, and gives a detailed overview how it fits into the framework of existing fiber or beam ...
Maximilian J. Grill, Wolfgang A. Wall, Christoph Meier   +2 more
doaj   +1 more source

"Bernoulli" Levitation

, 2002
"Bernoulli" levitation is the basis of many popular counter-intuitive physics demonstrations. However, few of these lend themselves to a quantitative description without recourse to computational fluid dynamics.
Bendall, Sarah, Kotlicki, Andrzej, Waltham, Chris   +2 more
core   +1 more source

Combination and application of machine learning and computational mechanics

Chinese Science Bulletin, 2019
With the steady development of computer science, machine learning and data science have made significant progress in recent decades. These techniques generally rely on a substantial amount of data samples to extract the abstract mapping hidden within the
Xiang Li, Ziming Yan, Zhanli Liu
semanticscholar   +1 more source

Local computation mechanism design [PDF]

Proceedings of the fifteenth ACM conference on Economics and computation, 2014
We introduce the notion of local computation mechanism design —designing game-theoretic mechanisms that run in polylogarithmic time and space. Local computation mechanisms reply to each query in polylogarithmic time and space, and the replies to different queries are consistent with the same global feasible solution.
Hassidim, Avinatan, Mansour, Yishay, Vardi, Shai   +2 more
openaire   +3 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

A QM/MM approach for the study of monolayer-protected gold clusters

, 2012
We report the development and implementation of hybrid methods that combine quantum mechanics (QM) with molecular mechanics (MM) to theoretically characterize thiolated gold clusters.
A Corma, A Venzo, A Warshel, AC Templeton, AK Rappé, ASK Hashmi, CJ Zhong, CM Aikens, DT Miles, F Weigend, G Henkelman, H Qian, I Garzón, J Akola, JF Parker, John A. Montgomery, José A. Gascón, JR Cheeseman, JTv Wijngaarden, L Fabris, M Dasog, M Haruta, MS Devadas, MW Heaven, MZ Zhu, NV Perera, O Lopez-Acevedo, PD Jadzinsky, RFW Bader, S Dapprich, Sandipan Banerjee, T Vreven, WD Cornell   +32 more
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Numerical investigation of pile foundation systems employing an enhanced embedded finite element

Frontiers in Built Environment
The design of large-scale pile foundation systems is routinely assisted by finite element simulations. To a large extent, both the modeling and the computational effort of such analyses are governed by the adopted pile modeling technique. The traditional
Andreas-Nizar Granitzer, Haris Felic, Johannes Leo, Alexander Stastny, Alexander Stastny, Franz Tschuchnigg   +5 more
doaj   +1 more source