Results 61 to 70 of about 3,809,966 (324)

Quantum Mechanics with Trajectories: Quantum Trajectories and Adaptive Grids [PDF]

, 2003
Although the foundations of the hydrodynamical formulation of quantum mechanics were laid over 50 years ago, it has only been within the past few years that viable computational implementations have been developed.
Bittner, Eric R., Wyatt, Robert E.
core   +2 more sources

Computational Fluid Dynamics

Radial Flow Turbocompressors, 2021
Contents: Finite-Element method and aspects for computer implementation, computa-tion of mechanical problems, coupled field problems (magnetic, mechanical and acoustic), optimization of modern mechatronic systems.
Prof. Manoj Kumar, Moharana, Prof. B. Kiran Naik, Prof, Kishore Singh, Patel   +5 more
semanticscholar   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Hydrodynamic Characteristics of Two Side-by-Side Cylinders at a Pitch Ratio of 2 at Low Subcritical Reynolds Numbers

Fluids, 2022
Isothermal turbulent flow around circular cylinders arranged side-by-side was numerically simulated on a commercial finite-volumes platform, ANSYS® CFX, version 2020 R2. The turbulence was modeled by using k-ω shear stress transport (k-ω SST).
Thiago Gomes, Jhon Goulart, Carla Anflor
doaj   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Transient dynamical-thermal-optical system modeling and simulation

Journal of the European Optical Society-Rapid Publications, 2021
In modern high resolution optical systems like astronomical telescopes or lithographic objectives, performance degradations can be caused by various disturbances.
Luzia Hahn, Peter Eberhard
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Asymptotically consistent and computationally efficient modeling of short-ranged molecular interactions between curved slender fibers undergoing large 3D deformations

Advanced Modeling and Simulation in Engineering Sciences
This article proposes a novel computational modeling approach for short-ranged molecular interactions between curved slender fibers undergoing large 3D deformations, and gives a detailed overview how it fits into the framework of existing fiber or beam ...
Maximilian J. Grill, Wolfgang A. Wall, Christoph Meier   +2 more
doaj   +1 more source

Local computation mechanism design [PDF]

Proceedings of the fifteenth ACM conference on Economics and computation, 2014
We introduce the notion of local computation mechanism design —designing game-theoretic mechanisms that run in polylogarithmic time and space. Local computation mechanisms reply to each query in polylogarithmic time and space, and the replies to different queries are consistent with the same global feasible solution.
Hassidim, Avinatan, Mansour, Yishay, Vardi, Shai   +2 more
openaire   +3 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source