Results 91 to 100 of about 297,450 (276)

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

Advanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich   +10 more
wiley   +1 more source

Quantifying Resource Use in Computations [PDF]

, 2009
It is currently not possible to quantify the resources needed to perform a computation. As a consequence, it is not possible to reliably evaluate the hardware resources needed for the application of algorithms or the running of programs. This is apparent
van Son, R. J. J. H.
core   +1 more source

Melt Electrowriting High Resolution Poly(ethylene‐co‐vinyl acetate) Scaffolds for Soft Tissue Engineering

Advanced Healthcare Materials, EarlyView.
This work pioneers melt electrowriting (MEW) of polyethylene vinyl acetate (PEVA) to fabricate ultra‐compliant, high‐resolution scaffolds. By integrating microscale precision with soft tissue‐like biomechanics, PEVA overcomes stiffness‐driven limitations of conventional MEW polymers, establishing a mechanically biomimetic platform for soft tissue ...
Finn Snow, Darcy De Rauch, Lilith Mabel Caballero Aguilar, Darcy Millett, Jasley Wilding McBride, David R Nisbet, Magdalena Kita, Elena Pirogova, Robert Michail Ivan Kapsa, Anita Quigley   +9 more
wiley   +1 more source

Vesicle and reaction-diffusion hybrid modeling with STEPS

Communications Biology
Vesicles carry out many essential functions within cells through the processes of endocytosis, exocytosis, and passive and active transport. This includes transporting and delivering molecules between different parts of the cell, and storing and ...
Iain Hepburn, Jules Lallouette, Weiliang Chen, Andrew R. Gallimore, Sarah Y. Nagasawa-Soeda, Erik De Schutter   +5 more
doaj   +1 more source

CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads

Advanced Healthcare Materials, EarlyView.
In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleen‐targeted expression, providing greater applications for ...
Eshan A. Narasipura, Vincent Fung, Rachel VanKeulen‐Miller, Palas B. Tiwade, Owen S. Fenton   +4 more
wiley   +1 more source

Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application

Advanced Materials, EarlyView.
This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong, You Zhou, Qingxiu Li, Wenyu Zhao, Sunyingyue Geng, Hangfei Li, Yan‐Bing Leng, Shirui Zhu, Guanglong Ding, Yongbiao Zhai, Ziyu Lv, Ye Zhou, Su‐Ting Han   +12 more
wiley   +1 more source

Structural plasticity controlled by calcium based correlation detection

Frontiers in Computational Neuroscience, 2008
Hebbian learning in cortical networks during development and adulthood relies on the presence of a mechanism to detect correlation between the presynaptic and the postsynaptic spiking activity.
Moritz Helias, Moritz Helias, Stefan Rotter, Stefan Rotter, Marc-Oliver Gewaltig, Marc-Oliver Gewaltig, Markus Diesmann, Markus Diesmann, Markus Diesmann   +8 more
doaj   +1 more source

Rethinking Extracellular Vesicle Signaling

Advanced Materials, EarlyView.
Extracellular vesicles enable cell communication beyond intracellular cargo delivery. This perspective highlights two plausible surface‐based signaling modes: “bind‐and‐stay” and “bind‐and‐leave.” Transient binding to multiple cells challenges the one‐vesicle‐one‐cell model.
Wojciech Chrzanowski, Joy Wolfram
wiley   +1 more source

Generic decoding of seen and imagined objects using hierarchical visual features

Nature Communications, 2017
Machine learning algorithms can decode objects that people see or imagine from their brain activity. Here the authors present a predictive decoder combined with deep neural network representations that generalizes beyond the training set and correctly ...
Tomoyasu Horikawa, Yukiyasu Kamitani
doaj   +1 more source

A reanalysis of “Two types of asynchronous activity in networks of excitatory and inhibitory spiking neurons” [version 1; referees: 2 approved]

F1000Research, 2016
Neuronal activity in the central nervous system varies strongly in time and across neuronal populations. It is a longstanding proposal that such fluctuations generically arise from chaotic network dynamics.
Rainer Engelken, Farzad Farkhooi, David Hansel, Carl van Vreeswijk, Fred Wolf   +4 more
doaj   +1 more source