Results 171 to 180 of about 126,855 (275)

Daily‐Life, Sensor‐Derived Tremor Measures Are Sensitive to Progression in Early Parkinson's Disease

Annals of Neurology, EarlyView.
Objective Sensitive outcome measures are critical for evaluating the efficacy of novel treatments for Parkinson's disease (PD). In this study, we assess the sensitivity to change of sensor‐derived daily‐life tremor measures over 2 years in unmedicated and medicated persons with early PD.
Nienke A. Timmermans, Ioan Gabriel Bucur, Diogo C. Soriano, Erik Post, Hayriye Cagnan, Sooyoon Shin, Max A. Little, Yordan P. Raykov, Bastiaan R. Bloem, Rick C. Helmich, Luc J.W. Evers   +10 more
wiley   +1 more source

Computational neuroscience: a frontier of the 21^st century. [PDF]

Natl Sci Rev, 2020
Wang XJ, Hu H, Huang C, Kennedy H, Li CT, Logothetis N, Lu ZL, Luo Q, Poo MM, Tsao D, Wu S, Wu Z, Zhang X, Zhou D.   +13 more
europepmc   +1 more source

Editorial: Neuromorphic and deep learning paradigms for neural data interpretation and computational neuroscience. [PDF]

Front Comput Neurosci
Zou C, Yuan R, Wen J.
europepmc   +1 more source

From computational neuroscience to intelligent robots and back

, 2017
The field of neurorobotics encompasses the intersection of computational neuroscience and robotics. The TUM-led neurorobotics subproject of the Human Brain Project is actively researching concepts within the field and developing the tools to allow ...
Knoll, Alois, Kuhn, Alexander, Sharma, Kenny, Akl, Mahmoud, Röhrbein, Florian   +4 more
core  

Monoallelic POLR3A Variants Cause Early‐Onset Peripheral Neuropathy

Annals of Neurology, EarlyView.
Objective Biallelic variants in genes encoding the RNA polymerase III complex (Pol III) cause a spectrum of neurological disorders primarily affecting the central nervous system. Monoallelic variants have been reported in the POLR3B subunit only, associated with neurodevelopmental disorder, epilepsy, and peripheral neuropathy.
Luiza L. P. Ramos, Jevin M. Parmar, Robin Wijngaard, Bianca R. Grosz, Tamas Lazar, Ligia Mateiu, Steve Vucic, Kishore R. Kumar, Dennis Yeow, Laura I. Rudaks, Lonneke de Boer, Annemarie de Vreugd, David A. Koolen, Thatjana Gardeitchik, Anita Cairns, Krishnan Iyengar, Fernando Kok, Fernanda Barbosa Figueiredo, Alzira Alves de Siqueira Carvalho, Luiz S. Mageste Barbosa, Rodrigo Rezende Arantes, Tyler Rehbein, Jordan E. Bontrager, Elizabeth P. Wood, Janet E. Sowden, Gavin Monahan, Meutia Kumaheri, Ivy Cuijt, Melina Ellis, Gonzalo Perez‐Siles, Elyshia McNamara, Ronald van Beek, Celine B. Meijers, Ivaylo Tournev, Stephan Zuchner, Shoshana J. Wodak, Clara D. M. van Karnebeek, Nigel Laing, Liana N. Semcesen, David A. Stroud, David N. Herrmann, Velina Guergueltcheva, Marina L. Kennerson, Machteld M. Oud, Gianina Ravenscroft, Ayse Candayan, Albena Jordanova   +46 more
wiley   +1 more source

Novel applications of machine learning and computational neuroscience models to neuroimaging in Parkinson's disease and related disorders. [PDF]

Front Aging Neurosci
Chougar L, Vo A, Lehéricy S, Dagher A.
europepmc   +1 more source

Cardiovascular Exercise Drives Neuroprotection in a Mouse Model of Spinocerebellar Ataxia 1 Via Rescue of Aberrant Splicing

Annals of Neurology, EarlyView.
Objective Spinocerebellar ataxia 1 (SCA1) is a fatal hereditary neurodegenerative disorder with no approved therapies, and gene‐targeting strategies have thus far failed in clinical trials. Exercise remains the only intervention shown to provide clinical benefit in patients with spinocerebellar ataxias (SCAs), yet the underlying mechanisms remain ...
Isabel Soto, Michael Bonomo, Brianna S. Nelthrope, Benjamin D. Carr, Emma Palmer, Mariana Sierra, Ilkim Erturk, David Peppercorn, Eleonor Cox, Tiare K. Vasconcellos, Henry L. Paulson, Hannah K. Shorrock, Sharan R. Srinivasan   +12 more
wiley   +1 more source

Forward and reverse engineering the pain system: from computational neuroscience to neuro-engineering. [PDF]

Pain
Mahajan P, Seymour B.
europepmc   +1 more source

30th Annual Computational Neuroscience Meeting: CNS*2021-Meeting Abstracts. [PDF]

J Comput Neurosci, 2021
europepmc   +1 more source

Trainee Poster Award on 28th Annual Computational Neuroscience Meeting CNS*2019

The poster “Arbor: A morphologically detailed neural network simulation library for modern high performance computer architectures” by Anne Küsters received the “Trainee Poster Award” by the Organisation for Computational Neurosciences on the 28th Annual
Küsters, Anne
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