Results 91 to 100 of about 33,138 (231)

Ultrafast oscillations in the human brain and their functional significance

Epilepsia, EarlyView.
Abstract Objective The upper frequency limit of human brain activity remains unknown. Using ultrahigh sampling rate (≥20 kHz) intracranial microelectroencephalography, this study aimed to systematically explore and quantitatively characterize brain field oscillations beyond the established high‐frequency oscillation range (>2 kHz), and to determine ...
Milan Brázdil, Vojtěch Trávníček, Jonathan Curot, Martin Pail, Monika Służewska‐Niedźwiedź, Robert Roman, Filip Plešinger, Emmanuel Barbeau, Michal Kucewicz, Petr Klimeš, Jan Cimbálník, Pavel Jurák, William C. Stacey, Gregory A. Worrell   +13 more
wiley   +1 more source

Comparison of volume‐ and surface‐based magnetic resonance imaging morphometry algorithms in the detection of focal cortical dysplasia

Epilepsia, EarlyView.
Abstract Objective Detection of focal cortical dysplasia (FCD) remains a major challenge in presurgical epilepsy diagnostics. Magnetic resonance imaging (MRI) morphometry increasingly improves lesion detection and postsurgical outcomes. The volume‐based Morphometric Analysis Program, version 2018 (MAP18) with integrated artificial neural network and ...
Lara Bücheler, Marco Reisert, Theo Demerath, Florian Mayer, Christian Moeller, Joshua Reß, Yiwen Li Hegner, Dirk‐Matthias Altenmüller, Victoria San Antonio‐Arce, Christian Scheiwe, Mukesch Shah, Jürgen Beck, Soroush Doostkam, Thomas Bast, Bernhard J. Steinhoff, Andreas Schulze‐Bonhage, Horst Urbach, Marcel Heers   +17 more
wiley   +1 more source

The dynamic functional connectivity peak index: Detection of interictal epileptic activity with fMRI

Epilepsia, EarlyView.
Abstract Objective Epileptogenic zone (EZ) localization is crucial for surgical treatment of patients with medication‐resistant epilepsy. Although simultaneous electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) can detect interictal discharges for EZ localization, clinical adoption is limited by the need for specialized ...
Lucas E. Sainburg, Alexandra Roche, Ghassan S. Makhoul, Baxter P. Rogers, Shawniqua Williams Roberson, Stefano Meletti, Anna E. Vaudano, Catie Chang, Dario J. Englot, Victoria L. Morgan   +9 more
wiley   +1 more source

A transdiagnostic conflict-square algorithm: a four-node computational framework for psychotherapy and functional diagnosis

Frontiers in Psychiatry
Clinical services need more than categorical labels to guide safe dosing, maintain alliance, and plan functional recovery. The Conflict-Square Algorithm (CSA) offers a compact bedside grammar for moment-to-moment decisions during psychotherapy ...
Eik Niederlohmann
doaj   +1 more source

Complementary predictive value of electromagnetic source imaging and hemodynamic responses in epilepsy surgery: A quantitative spatial analysis

Epilepsia, EarlyView.
Abstract Objective Accurate presurgical evaluation should assess not only the location but also the spatial extent of epileptic activity relative to the surgical cavity, a practical approximation of the epileptogenic zone. We evaluated how electromagnetic source imaging (EMSI) and hemodynamic responses to epileptic discharges relate to the surgical ...
Chifaou Abdallah, Edouard Delaire, Arielle Dascal, Aura González, Zhengchen Cai, Tanguy Hedrich, Hassan Khajehpour, Satoru Ikemoto, Masataka Tanaka, Boris C. Bernhardt, Eliane Kobayashi, Jean Gotman, Birgit Frauscher, Christophe Grova   +13 more
wiley   +1 more source

Insights into ANKRD11‐related epilepsy from 163 people

Epilepsia, EarlyView.
Abstract Objective Ankyrin repeat domain 11 gene (ANKRD11) is the key disease gene for autosomal dominant KBG syndrome, and a subset of affected individuals develop epilepsy. However, comprehensive characterization of epilepsy‐related phenotypes and genotype–phenotype correlations in ANKRD11 variant carriers remains limited.
Song Su, Jian Ma, Qi Zhang, Wandong Hu, Ying Ren, Wenchao Zhang, Hongwei Zhang   +6 more
wiley   +1 more source

Computational Psychiatry and the Placebo Effect in Psychosis. [PDF]

Biol Psychiatry Glob Open Sci, 2023
Atlas LY.
europepmc   +1 more source

Diagnostic yield and copy number variants findings in 219 adult patients with developmental and epileptic encephalopathy

Epilepsia, EarlyView.
Abstract In a clinical setting, exome sequencing (ES) with copy number variant (CNV) analysis is currently the most effective approach for developmental and epileptic encephalopathies (DEE). However, trio‐based ES is often not feasible in adults, its costs remain prohibitive in certain health care settings, and computational tools for CNV calling still
Laura Licchetta, Giulia Bruschi, Tania Giangregorio, Carlotta Stipa, Elisa Mannini, Raffaella Minardi, Barbara Mostacci, Valentina Tontini, Tommaso Pippucci, Francesca Bisulli, Pamela Magini   +10 more
wiley   +1 more source

Anterior cingulate cortex neuron subtypes differentially regulate seizures

Epilepsia, EarlyView.
Abstract Objective This study aimed to investigate the regulatory roles of distinct neuronal subtypes within the anterior cingulate cortex (ACC) in acute seizures and to identify cell type‐specific mechanisms underlying seizure modulation in this region. Methods Acute seizure models were established in mice via pentylenetetrazol injection.
Ziqian Yan, Ting Tang, Kaishan Wang, Bin Fu, Zesheng Li, Mingshan Liu, Hongyi Huang, Yanfeng Yang, Qiang Zheng, Yangmin Zheng, Yongzhi Shan, Yumin Luo, Guoguang Zhao   +12 more
wiley   +1 more source

Barriers and solutions to the adoption of translational tools for computational psychiatry. [PDF]

Mol Psychiatry, 2023
Benrimoh D, Fisher V, Mourgues C, Sheldon AD, Smith R, Powers AR.   +5 more
europepmc   +1 more source