Results 91 to 100 of about 8,550,305 (373)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
From computational science to Internetics: Integration of science with computer science [PDF]
Mathematics and Computers in Simulation, 2000 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +1 more source
GREENER principles for environmentally sustainable computational science
Nature Computational Science, 2023 Loïc Lannelongue +9 more
semanticscholar +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
MANIFESTO OF COMPUTATIONAL SOCIAL SCIENCE
Mediações: Revista de Ciências Sociais, 2013 The increasing integration of technology into our lives has created unprecedented volumes of data on society’s everyday behaviour. Such data opens up exciting new opportunities to work towards a quantitative understanding of our complex social systems ...
Rosaria Conte +13 more
doaj +1 more source
Computational challenges of systems biology [PDF]
, 2004 Progress in the study of biological systems such as the heart, brain, and liver will require computer scientists to work closely with life scientists and mathematicians.
Finkelstein, A. +6 more
core
Understanding Student Computational Thinking with Computational Modeling
, 2012 Recently, the National Research Council's framework for next generation science standards highlighted "computational thinking" as one of its "fundamental practices".
Aiken, John M. +6 more
core +1 more source
Computational Mathematics, Science and Engineering (CMSE): Establishing an Academic Department Dedicated to Scientific Computation as a Discipline [PDF]
, 2020 Dirk Colbry +3 more
openalex +1 more source
Editorial: Computational Proteomics and Integration of Data Resources for Advanced Studies in Life Sciences [PDF]
, 2021 Anna Marabotti +2 more
openalex +1 more source
Computational biomolecular science [PDF]
Proceedings of the National Academy of Sciences, 1998 In this century, the study of the molecules of life has transformed the practice of biology as a whole. Molecular thinking now influences the research agenda for scientists studying both the behavior of individual cells and organisms, and the relationships between organisms as in natural history.
openaire +2 more sources