Results 21 to 30 of about 624,297 (264)
Mathematical modeling based on ordinary differential equations: A promising approach to vaccinology
Human Vaccines & Immunotherapeutics, 2017 New contributions that aim to accelerate the development or to improve the efficacy and safety of vaccines arise from many different areas of research and technology.
Carla Rezende Barbosa Bonin +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Education Sciences, 2019 Science educators have begun to explore how students have opportunities to not only view and manipulate simulations, but also to analyze the complex sources of data they generate.
Joshua M. Rosenberg, Michael A. Lawson
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Improving Interoperability in Scientific Computing via MaRDI Open Interfaces
Journal of Open Research SoftwareMaRDI Open Interfaces is a software project aimed at improving reuse and interoperability in scientific computing by alleviating the difficulties of crossing boundaries between different programming languages, such as C, Julia, or Python, in which ...
Dmitry I. Kabanov +2 more
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The DEMO Quasisymmetric Stellarator
Energies, 2010 The NSTAB nonlinear stability code solves differential equations in conservation form, and the TRAN Monte Carlo test particle code tracks guiding center orbits in a fixed background, to provide simulations of equilibrium, stability, and transport in ...
Geoffrey B. McFadden, Paul R. Garabedian
doaj +1 more source
Computational Science: An Intermingling of Science, Mathematics, and Computer Science [PDF]
, 2006 The development of a full undergraduate program in computational science, with both a broad-swath academic plan and four specialization plans, one each in biochemistry, chemistry, earth sciences, and physics, is described. The reasons behind the establishment of the program are presented, and the evolution of the program over the past five years is ...
openaire +1 more source
The Science of Computer Science: Closing Statement [PDF]
Ubiquity, 2014 Where does computer science as an intellectual discipline fit in human discourse? Over a dozen contributors have looked at this question of identity from as many viewpoints. In this closing statement, we emphasize six themes running through these 16 commentaries and draw some conclusions that seem to be supported by the symposium.
Richard T. Snodgrass, Peter J. Denning
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FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Rethinking resource allocation in science
Ecology and Society, 2019 Many funding agencies rely on grant proposal peer review to allocate scientific funding, i.e., researchers compete for funding by submitting proposals that are reviewed and ranked by committees of their peers.
Johan Bollen +3 more
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