Results 171 to 180 of about 2,703,446 (282)
A Comprehensive Review of Biotechnological Innovations in Valorization of Food Waste: Enhancing Nutritional, Techno‐Functional Properties, and Process Optimization for Sustainable Product Development
Food Frontiers, EarlyView.This review highlights recent biotechnological innovations in the valorization of food waste through enzyme‐assisted processing and microbial fermentation to enhance nutritional, techno‐functional, and shelf‐stable properties for developing sustainable, plant‐based functional foods and nutraceuticals.Md. Sakhawot Hossain, Md Abdul Wazed, Mst. Sultana Akhter Preya, Zakia Sultana, Md. Mostafa Kamal, Tanvir Ahmad, Islam Md Shimul +6 morewiley +1 more sourceVanillin Modulates the Sedative Effect of Diazepam, Possibly Through GABAergic Interaction Pathways in Thiopental Sodium‐Induced Sleeping Mice
Food Safety and Health, EarlyView.Vanillin showed moderate sedative and modulatory synergistic activities on diazepam in thiopental sodium‐induced sleeping mice. These effects are implicated with GABAergic intervention. ABSTRACT
Insomnia is a common sleep disorder affecting approximately 10% of adults.Salehin Sheikh, Md. Shimul Bhuia, Raihan Chowdhury, Md. Sakib Al Hasan, Most. Israt Jahan Oni, Imam Hossen Rakib, Mir Imran Alim, Jakia Sultana, Muhammad Torequl Islam +8 morewiley +1 more sourceArtificial Intelligence Revolutionizes Anti‐Infective Drug Discovery: From Target Identification to Lead Optimization
iMetaMed, EarlyView.Artificial intelligence (AI) technology is revolutionizing antimicrobial drug development. In response to increasingly severe antimicrobial resistance challenges, AI can efficiently predict pathogen evolutionary trends, identify potential drug targets, and accelerate compound design and optimization, thereby significantly shortening the development ...Kexin Li, Quan Yuan, Chang Qi, Ying Shi, Hong Yang, Anqi Lin, Shuofeng Yuan +6 morewiley +1 more sourcePotassium Sorbate Triggers Kidney Injury via Dysregulated Intercellular Communication: A Study Combining Network Toxicology, Machine Learning, Molecular Docking, and Single‐Cell RNA Sequencing
iMetaMed, EarlyView.Amyloid precursor protein (APP)‐mediated endothelial‐immune cell crosstalk is a novel mechanism for potassium sorbate‐induced renal injury. Multi‐omics integration (network toxicology, machine learning, scRNA‐seq) uncovers this interaction via APP‐CD74/PTGER2 axes, linking oxidative stress and inflammation to renal damage. ABSTRACT
Acute kidney injury (Yimao Wu, Yalun Liang, Jintao Liang, Gokhan Zengin, Qian Zhang, Meng‐Yao Li +5 morewiley +1 more sourceMicrobiota‐gut‐brain axis multi‐organ chip construction and applications in drug evaluation
iMetaOmics, EarlyView.Microbiota‐gut‐brain axis multiorgan chip and its applications in drug evaluation. The chip includes essential biological components such as gut microbiota, gut barrier, blood‐brain barrier (BBB), and brain. This integrated platform incorporates neural (blue), endocrine (yellow), immune (pink), and metabolic (green) pathways to investigate the impact ...Yue Tang, Hewen Chen, Ziyue Zhao, Xuesong Kang, Wenxin Wang, Kun Dai, Yufei Guo, Axin Liang, Aiqin Luo, Zikai Hao +9 morewiley +1 more sourceiMeta Conference 2025: Creating high‐impact international journals
iMeta, EarlyView.The iMeta Conference 2025, part of the iMeta Conference series, themed “Creating High‐Impact International Journals,” held at the Huangjiahu Campus of Hubei University of Chinese Medicine from August 23rd to 25th, 2025, and focused on frontier topics such as microbiology, medicine, traditional Chinese medicine, botany, and research career development ...Zhihao Zhu, Lin Zhang, Xiaofang Yao, Meiyin Zeng, Yao Wang, Hao Luo, Yuanping Zhou, Tianyuan Zhang, Jiani Xun, Defeng Bai, Haifei Yang, Shanshan Xu, Yang Zhou, Yunyun Gao, Jinbo Xu, Wei Han, ZiAng Shen, Bangzhou Zhang, Tengfei Ma, Xiu‐Lin Wan, Chuang Ma, Fengjiao Hui, Hao Bai, Lijing Bai, Qing Bai, Qiangguo Bao, Guodong Cao, Peng Cao, Qiqi Cao, Hu Chen, Jiawen Chen, Jiaxu Chen, Lihua Chen, Tingting Chen, Yi Chen, Haipeng Cui, Shaoxing Dai, Xi‐Jian Dai, Xiaofeng Dai, Yanqi Dang, Lei Deng, Yun Deng, Xia Ding, Binhua Dong, Ling Dong, Shujie Dou, Hongzhi Du, Zhencheng Fang, Xiaoxiao Feng, Min Fu, Yuan Gao, Wenping Gong, Xiang Guo, Wenjie Han, Zikai Hao, Zheng‐Guo He, Haibo Hu, Haiming Hu, Xuefei Hu, Liang Huang, Xianya Huang, Xueting Huang, Haochen Hui, Dingjiacheng Jia, Aimin Jiang, Di Jiang, Kun Jiang, Dewei Jiang, Ying Jin, Kunyang Lai, Chun Li, Feng Li, Fuyong Li, Jing Li, Juan Li, Junling Li, Kui Li, Ling Li, Moli Li, Peiwu Li, Peng Li, Runze Li, Shengnan Li, Shujin Li, Wanting Li, Wenting Li, Xiaojing Li, Xinrui Li, Xuemeng Li, Qiqi Liang, Xiaoping Liao, Boyang Liu, Canzhao Liu, Chang Liu, Duanrui Liu, Furong Liu, Jianjun Liu, Jinyao Liu, Siqi Liu, Tianyang Liu, Wenjuan Liu, Yan Liu, Yang Liu, Yi Liu, Yuan Liu, Yunhuan Liu, Zhipeng Liu, Zhiyong Liu, Xin Lu, Xiao Luo, Guanju Ma, Jialin Meng, Yuanfa Meng, Runyu Miao, Linxuan Miao, Yawen Ni, Dongze Niu, Tingting Niu, Hongzhao Pan, Guoqiang Qin, Tiantian Qiu, Yueping Qiu, Hui Qu, Linghang Qu, Na Ren, Qiang Sun, Run Shang, Peize She, Xihui Shen, Bohan Shi, You Shu, Jiawei Song, Weibin Song, Qi Su, Qingzhu Sun, YuPing Sun, Zijin Sun, Bufu Tang, Deqin Tang, Hua Tang, Yongfu Tao, Teng Teng, Yanye Tu, Cheng Wang, Hui Wang, Yunhao Wang, Chunli Wang, Dingjie Wang, Gang Wang, Jin Wang, Kaiyi Wang, Mingbang Wang, Shan Wang, Shixiang Wang, Xiaojie Wang, Xing‐Chang Wang, Yunzhe Wang, Jiale Wang, Zheng Wang, Weijie Wang, Yongjun Wei, Wei Xu, Fan Wu, Junling Wu, Shijuan Wu, Jian Xiao, Weihua Xiao, Yang Xiao, Xi Xiong, Xue Xiong, Feng Xu, Junyu Xu, Wen Xu, Jun Xu, Yao Xu, Jun Yan, Lutian Yao, Jia Yang, Lulu Yang, Xingzhen Yang, Naiyi Yin, Hua You, Min You, Ting Yu, Yongyao Yu, Renqiang Yu, Shuofeng Yuan, Chaoxiong Yue, Xiaoya Zeng, Andong Zha, Leilei Zhai, Chi Zhang, Dong Zhang, Hengguo Zhang, Heng Zhang, Hongyu Zhang, Jiahao Zhang, Jinyang Zhang, Lishan Zhang, Qi Zhang, Xiang Zhang, Xiangyu Zhang, Xuelei Zhang, Yancong Zhang, Yuan Zhang, Zhenyu Zhang, Jiwei Zhao, Jingxuan Zhao, Kai Zhao, Mingjuan Zhao, Yi Zhao, Yunxiang Zhao, Jixin Zhong, Ling Zhong, Xiangjian Zhong, Dan Zhou, Wei Zhou, Wen Zhou, Yiqian Zhou, Zhemin Zhou, Shiquan Zhu, Shuang‐Jiang Liu, Suyin Feng, Shuangxia Jin, Chuanxing Xiao, Ziheng Wang, Peng Luo, Tong Chen, Gang Chen, Yong‐Xin Liu +229 morewiley +1 more sourceTargetGen‐RNN model discovers novel antibiotic compound targeting drug‐resistant Staphylococcus aureus
Interdisciplinary Medicine, EarlyView.TargetGen‐recurrent neural network (RNN), an advanced generative model, generated 28,708 unique and novel compounds, identifying SAK‐2970 as a potent antibiotic against drug‐resistant Staphylococcus aureus. Exhibiting strong biofilm inhibition, high therapeutic efficacy, and minimal systemic toxicity in vivo, SAK‐2970 highlights its safety and clinical Shakeel Ahmad Khan, Adnan Shakoor, Sadia Kanwal +2 morewiley +1 more source
