Results 201 to 210 of about 73,306 (292)

Methods in Ecology and Evolution editorial on animal and plant ethics in research

Methods in Ecology and Evolution, EarlyView.
Graziella Iossa, Tamara Contador, Eleanor Drinkwater, Jennifer Meyer, Joseph Mwanzia Nguta, Huijie Qiao, Elva J. H. Robinson, Ricardo Rozzi, Lynne U. Sneddon, Carl D. Soulsbury, Baojun Sun, Aaron M. Ellison   +11 more
wiley   +1 more source

Comparative analysis of metabolic and functional cardiac alterations in diet‐ and genetically induced mouse models of cardiac dysfunction

The FEBS Journal, EarlyView.
Dietary and genetic stress trigger different routes to heart failure. In mice, a carbohydrate‐free high‐fat diet caused mitochondrial dysfunction and impaired energy production with preserved pumping function, while genetic obesity led to heart enlargement, fibrosis, and reduced function.
Christiane Ott, Patricia Baumgarten, Thorsten Henning, Daniela Weber, Iwona Wallach, Jana Grune, Ulrich Kintscher, Hermann‐Georg Holzhütter, Tilman Grune, Nikolaus Berndt   +9 more
wiley   +1 more source

Aggregating data for computational toxicology applications: The U.S. Environmental Protection Agency (EPA) Aggregated Computational Toxicology Resource (ACToR) System. [PDF]

Int J Mol Sci, 2012
Judson RS, Martin MT, Egeghy P, Gangwal S, Reif DM, Kothiya P, Wolf M, Cathey T, Transue T, Smith D, Vail J, Frame A, Mosher S, Hubal EAC, Richard AM.   +14 more
europepmc   +1 more source

Bony fish genomes: Status and gaps

Journal of Fish Biology, EarlyView.
Abstract Bony fish constitute an exceptionally species‐rich group of aquatic vertebrates, comprising more than 95% of all living fish. The adaptive processes on the diversity of environments they inhabit make them a highly diverse group from taxonomic, morphological and evolutionary standpoints.
Noelia Pérez‐Pereira, Carmen Bouza, Paulino Martínez, Diego Robledo   +3 more
wiley   +1 more source

Associations of Adiposity With Gut Microbiota Composition Among Adults—Results From a Federated Analysis of Individual Participant Data From Eight European Observational Studies

Obesity Reviews, EarlyView.
ABSTRACT Gut microbiota may contribute to the adiposity‐associated disease risk, but human studies reported inconsistent associations of adiposity with gut microbiota composition. We examined associations of body mass index (BMI) with alpha diversity and relative microbial abundance at the phylum and genus taxonomic levels (based on 16S rRNA amplicon ...
Carolina Schwedhelm, Mariona Pinart, Sofia K. Forslund‐Startceva, Kolade Oluwagbemigun, Andreas Dötsch, Kristina Schlicht, Florian Schwarz, Sofia M. Siampani, Demetris Avraam, Maria De Angelis, Jildau Bouwman, Patrizia Brigidi, Giovanna Caderni, Francesco Maria Calabrese, Rafael R. C. Cuadrat, Carlotta De Filippo, Francesca De Filippis, Danilo Ercolini, Marco Fabbrini, Matthias Laudes, Ute Nöthlings, Serdar Özsezen, Itai Sharon, Matthias B. Schulze, Silvia Turroni, Francesco Vitali, Tobias Pischon, Katharina Nimptsch   +27 more
wiley   +1 more source

Computational modelling and network medicine in drug toxicology and clinical pharmacovigilance. [PDF]

J Transl Med
Zhao Q, Li X, Balan V.
europepmc   +1 more source

The Price of Prosperity? A Historical Account of Regulating Industrial Pollution in the Netherlands

Regulation &Governance, EarlyView.
ABSTRACT Regulatory governance and state‐corporate crime studies link persistent industrial pollution to long‐term regulatory–industry interactions, yet little is known about how these interactions evolve and become entrenched. This article examines two enduring cases of industrial pollution in the Netherlands—Hoogovens/Tata Steel and DuPont de Nemours/
Karin van Wingerde, Lieselot Bisschop, Sammie Verbeek, Julie Le Sage   +3 more
wiley   +1 more source

Potential for Computational Genotoxicity: A Report on Symposium 3 of the 53rd Annual Meeting of the Japanese Environmental Mutagen and Genome Society (JEMS), 2024. [PDF]

Genes Environ
Koyama N, Furuhama A, Kruhlak NL, Shinada NK, Izawa K.   +4 more
europepmc   +1 more source

Fosmidomycin for the Treatment of Canine Otitis Externa: A Randomised, Double‐Blinded, Controlled ‘Split Body’ Clinical Trial

Veterinary Dermatology, EarlyView.
ABSTRACT Background Targeted antimicrobial therapy for canine otitis externa (OE) represents an opportunity for antimicrobial stewardship. Fosmidomycin selectively inhibits the non‐mevalonate pathway for isoprenoid biosynthesis utilised by canine‐adapted, and not human‐adapted, staphylococci.
Lindsey E. Citron, Darko Stefanovski, Youwen You, Rachel Proctor, Donna Watson, Julie Randall, Christine L. Cain   +6 more
wiley   +1 more source

Computational pharmacovigilance of Lifitegrast in dry eye disease using machine learning and network toxicology. [PDF]

NPJ Digit Med
Li L, Jing S, Zhao X, Zhu X, Liang C, Shi L, Zhou P, Xie K, Jin B, Zhu H, Wang Y, Jin X, Du L, Yang P.   +13 more
europepmc   +1 more source