Results 211 to 220 of about 2,598,515 (356)

Ibuprofen‐Functionalized Alkyl α‐hydroxy Methacrylate‐Based Polymers

ChemistryOpen, EarlyView.
This work describes the synthesis and evaluation of novel alkyl α‐hydroxymethacrylate‐based ibuprofen‐functionalized prodrugs to improve the bioavailability, decrease toxicity, and control drug release. Novel alkyl α‐hydroxymethacrylate‐based prodrugs are prepared to improve bioavailability, decrease toxicity, and control drug release.
Burcu Balaban, Seckin Altuncu, Aleyna Esenturk, Simay Denizkusu, Ece Sabuncu, Hande Sipahi, Duygu Avci   +6 more
wiley   +1 more source

Profiling animal toxicants by automatically mining public bioassay data: a big data approach for computational toxicology. [PDF]

PLoS One, 2014
Zhang J, Hsieh JH, Zhu H.
europepmc   +1 more source

Combined effects and potential mechanisms of phthalate metabolites on serum sex hormones among reproductive-aged women: An integrated epidemiology and computational toxicology study

Xiaoqian Li, Na Zheng, Wenhui Zhang, Yan Yu, Yunyang Li, Siyu Sun, Yining Ji, Sujing Wang   +7 more
openalex   +1 more source

Synthesis and Characterization of Co(II), Cu(II), and Ni(II) Complexes of 2,2′‐Bipyridine‐4,4′‐Dicarboxamide Ligands: Antibacterial Evaluation Against Resistant Bacteria and Enzyme Inhibition

ChemistryOpen, EarlyView.
Two new 2,2′‐bipyridine‐4,4′‐dicarboxamide ligands and their Co(II), Cu(II), and Ni(II) complexes are synthesized and characterized. The L2‐Co complex shows strong antibacterial activity against Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa.
Hussein Alchurak, Aseel Almadhoun, İsmail Yılmaz, Raneem Mamoun Ali Nour, Müslüm Kuzu, Hasan Solmaz   +5 more
wiley   +1 more source

<strong>Ecotoxicological assessment of pharmaceuticals using computational toxicology approaches: QSTR and interspecies QTTR modelling</strong>

, 2018
Kunal Roy, Kabir Khan, Supratik Kar, Hans Sanderson, Jerzy Leszczyński   +4 more
openalex   +2 more sources

Evaluation of the Sedative Activity of Naringenin: In Vivo Study with Pharmacokinetics and Molecular Docking Insights

ChemistryOpen, EarlyView.
The study investigates the sedative potential of naringenin (NAR) through in vivo and in silico approaches. NAR significantly enhances sleep duration and reduces latency in mice, especially when combined with diazepam. Molecular docking shows strong binding to GABAA receptors, suggesting a GABAergic mechanism.
Dipu Bishwas, Md. Shimul Bhuia, Salehin Sheikh, Mohammed Alfaifi, Abdul Malik, Nikhat J. Siddiqui, Divya Jain, Mehedi Hasan Bappi, Muhammad Torequl Islam   +8 more
wiley   +1 more source

A ROLE OF AYURINFORMATICS COMPUTATIONAL TOXICOLOGY STUDY IN AGADATANTRA: A REVIEW

Sunita Khuntey, SR Inchulkar, Khushboo Karte   +2 more
openalex   +1 more source

Artificial intelligent for biomaterials and tissue engineering

Journal of Intelligent Medicine, EarlyView.
Xiaosong Gu
wiley   +1 more source

Essential Oil Profiles of Lippia turbinata (Verbenaceae) from Argentina: Insights from a Systematic Review and Meta‐Analysis

ChemistryOpen, EarlyView.
This study systematically reviews essential oil (EO) profiles of Lippia turbinata (Verbenaceae) populations from Argentina. A meta‐analysis reveals significant chemical variability and distinct chemotypes, primarily defined by limonene, carvone, β‐caryophyllene, and caryophyllene oxide.
Fernando Livio Corzo, Franco Emmanuel Calvo, Emilio Fernando Lizarraga, Guillermo Emilio Marcial, Maria Ines Mercado   +4 more
wiley   +1 more source

Integrative network and computational toxicology reveal the molecular mechanisms in PFOA-induced spermatogenic disorder

Yüjia Luo, Ensheng Xue, Yixiang Zhao, Huimin Lu, Di Xiang, Yuanyuan Zhou, Junfeng Zhan, Zhean Li, Fei Sun   +8 more
openalex   +1 more source