Results 201 to 210 of about 1,723,253 (280)

Methomyl resistance in Dalbulus maidis (Hemiptera: Cicadellidae): selection, inheritance and multiple‐resistance

Pest Management Science, EarlyView.
The inheritance of methomyl resistance in Dalbulus maidis is autosomal, incompletely dominant and polygenic. No cross‐resistance was found between methomyl and chlorfenapyr, cyantraniliprole and isocycloseram. Abstract BACKGROUND Acetylcholinesterase (AChE) inhibitor insecticides have been important tools for the management of Dalbulus maidis in Brazil;
Matheus Gerage Sacilotto, Gabriel Silva Dias, Mariana Yuki Iuanami, Celso Omoto   +3 more
wiley   +1 more source

Identifying resistance‐conferring cytochrome P450s in weeds: experimental strategies and practical considerations

Pest Management Science, EarlyView.
Identifying resistance‐conferring cytochrome P450s requires integrating weed characterization, gene discovery and functional validation. No single approach is sufficient to distinguish causal resistance genes from herbicide‐metabolizing enzymes. Abstract Cytochrome P450 monooxygenases (P450s) play a pivotal role in metabolic herbicide resistance, yet ...
Satoshi Iwakami, Takuya Yamaguchi
wiley   +1 more source

Characterization of a novel R98Q mutation that confers resistance to sulfentrazone in common ragweed (Ambrosia artemisiifolia) populations from Michigan

Pest Management Science, EarlyView.
Field‐collected Ambrosia artemisiifolia populations from Michigan, USA, soybean fields exhibited strong resistance to the protoporphyrinogen IX oxidase (PPO)‐inhibiting herbicide sulfentrazone and reduced sensitivity to fomesafen. Target‐site analysis identified a novel Arg‐98‐Gln (R98Q) substitution in PPO2, co‐occurring with the previously reported ...
Sara Álvarez‐Rodríguez, Michael Ozolins, Aimone Porri, Jens Lerchl, Eric Patterson   +4 more
wiley   +1 more source

Guest Editorial: Advances in Computational Toxicology [PDF]

Molecular Informatics, 2013
openaire   +2 more sources

Automatic insect identification, counting, and monitoring techniques: a review

Pest Management Science, EarlyView.
Automated insect monitoring increasingly integrates optical, acoustic, infrared, radar, electrostatic, and biosensing technologies with artificial intelligence. No single approach is universally optimal; reliable deployment depends on task‐specific validation, representative datasets, robustness under field conditions, energy autonomy, connectivity ...
Mariano González García, Juan Carlos Noguera Polania, Rosana González Combarros, José Ignacio López Sánchez   +3 more
wiley   +1 more source

Dehydrocostus Lactone Suppresses Hepatocellular Carcinoma by Inhibiting Protein Tyrosine Kinase‐7 Mediated β‐Catenin Signaling

Phytotherapy Research, EarlyView.
Schematic summary of the experimentally supported mechanism of DHL in hepatocellular carcinoma. Dehydrocostus lactone (DHL), a sesquiterpene lactone derived from Aucklandia lappa, directly engages protein tyrosine kinase 7 (PTK7), as supported by molecular docking, CETSA, and DARTS assays.
Xiwen Fan, Junhui Li, Yu Qiao, Yuwen Zhong, Xuecheng Ge, Yaoshuai Zhang, Zishu Wang, Feng Qian, Weixin Ren   +8 more
wiley   +1 more source

Baicalein Sensitizes Radioresistant BT549 and MCF7‐R Breast Cancer Cells by Modulating Rac1 Signaling

Phytotherapy Research, EarlyView.
ABSTRACT Radioresistance remains a key barrier in breast cancer (BC) treatment. Baicalein, a flavonoid from Scutellaria baicalensis, has shown potential to enhance radiosensitivity. This study investigates its efficacy and mechanism in radioresistant BC models. Radioresistant BC cell models were established via fractionated irradiation and validated by
Zitong Zhao, Zhangyun Li, Quanzhou Peng, Shuqun Zhang   +3 more
wiley   +1 more source

Transcriptome Inference and Systematic Approaches to Investigate TCM Compounds With Beneficial Metabolic Effects

Phytotherapy Research, EarlyView.
ABSTRACT Obesity is a major risk factor for type 2 diabetes. Some traditional Chinese medicine (TCM) compounds can improve obesity by increasing energy consumption. This study aimed to identify and verify TCM compounds that promote adipose thermogenesis to alleviate obesity via transcriptomic analysis, molecular docking, network pharmacology, and ...
Jing Li, Yang‐Chi‐Dung Lin, Hsi‐Yuan Huang, Jihang Chen, Huali Zuo, Yun Tang, Hsien‐Da Huang   +6 more
wiley   +1 more source

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

Phytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia, Despoina Pantazi   +1 more
wiley   +1 more source

Baicalin Induces Ferroptosis in Breast Cancer Through a Novel STAT3/HO‐1/GPX4 Regulatory Axis

Phytotherapy Research, EarlyView.
BA inhibits STAT3 phosphorylation and activation in BC cells, accompanied by decreased expression of HO‐1 and GPX4. Reduced GPX4 activity impairs lipid peroxide clearance, promoting ROS accumulation and lipid peroxidation, which ultimately triggers ferroptosis and inhibits cell proliferation.
Tingting Guo, Fansu Meng, Detang Li, Maciej Mazur, Alicia Marcelina Díaz García, Mulazim Hussain Asim, Zhong Chen, Yiqi Chen, Yixuan Lin, Zhenjiang Yang, Panpan Wang, Yu Cai   +11 more
wiley   +1 more source