Results 81 to 90 of about 69,485 (336)
Toxicology testing steps towards computers [PDF]
Lab Animal, 2019 Can the computer eliminate the lab animal? As computational methods become more advanced and data more freely available, in silico modeling approaches have growing potential to help reduce the number of animals needed to test chemical toxicity.
openaire +3 more sources
Advanced Science, EarlyView.Researchers developed SCORCH2, an advanced machine‐learning scoring function for virtual screening that combines two complementary XGBoost models to re‐evaluate protein‐ligand binding plausibility. The method demonstrates superior performance on standard benchmarks, shows excellent generalization to previously unseen protein targets, and provides ...
Lin Chen +3 more
wiley +1 more source
Mycotoxin exposure and human cancer risk : a systematic review of epidemiological studies
, 2020 In recent years, there has been an increasing interest in investigating the carcinogenicity of mycotoxins in humans. This systematic review aims to provide an overview of data linking exposure to different mycotoxins with human cancer risk. Publications (
Castegnaro M. +16 more
core +2 more sources
Bistable equilibrium points of mercury body burden [PDF]
, 2007 In the last century mercury levels in the global environment have tripled as a result of increased pollution from industrial, occupational, medicinal and domestic uses \cite{BaMe03}. Glutathione is known to be the main agent responsible for the excretion
Boulos, Areen, Owhadi, Houman
core +2 more sources
Advanced Science, EarlyView.This study presents a novel and facile thickness‐modulated 4D bioprinting approach using a smart bioink made of gelatin, GelMA, and MXene. Leveraging computational models, it creates living constructs with programmable unidirectional and bidirectional curvatures under a single UV exposure.
Jiahui Lai +7 more
wiley +1 more source
Zinc Grid Based Transparent Electrodes for Organic Photovoltaics
Advanced Energy Materials, EarlyView.A transparent flexible electrode based on an embedded zinc grid with ≈1 µm linewidth is reported, and its utility as a drop‐in replacement for indium‐tin oxide coated glass electrodes in organic photovoltaic devices is demonstrated. The zinc grids are fabricated using the unconventional approach of condensation coefficient modulation, using a ...
Philip Bellchambers +8 more
wiley +1 more source
Analysis of biomarker utility using a PBPK/PD model for carbaryl
Frontiers in Pharmacology, 2014 There are many types of biomarkers; the two common ones are biomarkers of exposure and biomarkers of effect. The utility of a biomarker for estimating exposures or predicting risks depends on the strength of the correlation between biomarker ...
Martin Blake Phillips +3 more
doaj +1 more source
Computational and Toxicological Evaluation of Thiamethoxam as Nicotinic Acetylcholine Receptor Modulator Against Cowpea Aphid, Aphis craccivora Koch. [PDF]
, 2023 Mohamed Abdelmoteleb +3 more
openalex +1 more source
Intelligent Theranostic Systems Enabled by Aggregation‐Induced Emission in Precision Medicine
Aggregate, EarlyView.Aggregation‐induced emission (AIE) luminogens are driving a new generation of intelligent theranostic systems that integrate high‐fidelity imaging and multifunctional therapy. This review highlights how AIEgens, through restriction of intramolecular motion (RIM), enable deep‐tissue NIR‐II imaging, ultrasensitive biosensing, CRISPR‐assisted gene ...
Qinqin Huang +7 more
wiley +1 more source
Advanced Intelligent Discovery, EarlyView.This study applies QSAR‐based new approach methodologies to 90 synthetic tattoo and permanent makeup pigments, revealing systemic links between their physicochemical properties and absorption, distribution, metabolism, and elimination profiles. The correlation‐driven analysis using SwissADME, ChemBCPP, and principal component analysis uncovers insights
Girija Bansod +10 more
wiley +1 more source