Results 101 to 110 of about 21,882 (246)

In Vitro and Predictive Computational Toxicology Methods for the Neurotoxic Pesticide Amitraz and Its Metabolites. [PDF]

Brain Sci, 2023
Giorgini M, Taroncher M, Ruiz MJ, Rodríguez-Carrasco Y, Tolosa J.   +4 more
europepmc   +1 more source

The gut microbiome and drug‐resistant epilepsy: Microbiome–antiseizure medication interactions and implications for pharmacoresistance

Epilepsia Open, EarlyView.
Abstract Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy and represents a major unmet clinical need. While traditional hypotheses of pharmacoresistance have focused on alterations in drug targets, efflux transporter overexpression, and intrinsic disease severity, the gut microbiome has recently emerged as a ...
Khaled Zammar, Majd A. AbuAlrob, Musab Ali, Simona Lattanzi, Boulenouar Mesraoua   +4 more
wiley   +1 more source

A Statistical Exploration of QSAR Models in Cancer Risk Assessment: A Case Study on Pesticide-Active Substances and Metabolites

Toxics
Data generated using new approach methodologies (NAMs), including in silico, in vitro, and in chemico approaches, are increasingly important for the hazard identification of chemicals.
Serena Greco, Cecilia Bossa, Chiara Laura Battistelli, Alessandro Giuliani   +3 more
doaj   +1 more source

Comparing Transcriptomic Responses to Chemicals Across Six Species Using the EcoToxChip RNASeq Database

Environmental Toxicology and Chemistry, EarlyView.
Abstract The EcoToxChip project includes RNA‐sequencing data from experiments involving model (Japanese quail, fathead minnow, African clawed frog) and ecological (double‐crested cormorant, rainbow trout, northern leopard frog) species at multiple life stages (whole embryo and adult) exposed to eight chemicals of environmental concern known to perturb ...
Krittika Mittal, Jessica Ewald, Doug Crump, Jessica Head, Markus Hecker, Natacha Hogan, Jianguo Xia, Niladri Basu   +7 more
wiley   +1 more source

Exercising electrocardiograms from Thoroughbred racehorses with exercise associated sudden death

Equine Veterinary Journal, EarlyView.
Abstract Background Exercise associated sudden death (EASD), defined as a fatal collapse in a closely monitored and previously presumed clinically healthy horse that occurs during exercise or within approximately 1 h after exercise, is disproportionately more common in equine than in human athletes.
Cristobal Navas de Solis, M. Durando, L. Nath, S. Durward‐Akhurst   +3 more
wiley   +1 more source

Use of computational toxicology tools to predict in vivo endpoints associated with Mode of Action and the endocannabinoid system: A case study with chlorpyrifos, chlorpyrifos-oxon and ^Δ9Tetrahydrocannabinol. [PDF]

Curr Res Toxicol, 2022
Silva M, Kwok RK.
europepmc   +1 more source

Trendelenburg positioning with or without norepinephrine infusion for haemodynamic support in anaesthetised hypovolemic horses

Equine Veterinary Journal, EarlyView.
Abstract Background Intraoperative haemorrhage during equine anaesthesia is a rare but potentially fatal complication requiring prompt haemodynamic support. Postural manoeuvres such as Trendelenburg (TL) positioning and vasopressor support augment venous return and improve cardiac output (CO), yet their efficacy in anaesthetised hypovolemic horses ...
Vaidehi V. Paranjape, Klaus Hopster, Ismar Lutvikadic, Bernd Driessen   +3 more
wiley   +1 more source

Risk factors for horse falls in British jump racing (2010–2023)

Equine Veterinary Journal, EarlyView.
Abstract Background Horse falls are an important safety and welfare concern in jump racing, as they are associated with an increased risk of equine fatality and injury, as well as jockey injury. Objectives To identify risk factors for horse falls in British jump racing. Study Design Retrospective cohort.
S. E. Allen, S. Taylor, J. Given, K. L. P. Verheyen   +3 more
wiley   +1 more source

Using a wearable electrocardiogram (ECG) patch adapted for 7‐day monitoring in the horse

Equine Veterinary Journal, EarlyView.
Abstract Background Arrhythmias can cause poor performance and sudden death in horses. Long‐term (>24 h) electrocardiogram (ECG) monitoring has been used to identify arrhythmias in humans and is superior to short‐term monitoring for transient arrhythmia detection. Televet is the current equine gold‐standard ECG device. The Cardea SOLO™ (CS) is a single‐
Tatiana Delecave Dias, Robert G. Hauser, Kendall Blanchard Cleary, Sian Durward‐Akhurst   +3 more
wiley   +1 more source

A High‐Efficiency Yet Sustainable Fresh‐Keeping Strategy Inspired by Calyx of Physalis peruviana

Exploration, EarlyView.
This study presents a sprayable, calyx‐inspired food wrap engineered for safety and sustainability using handheld electrospraying. The wrap forms a health‐critical protective barrier with high antiviral and antibacterial efficacy, excellent breathability, and long‐term fresh‐keeping performance.
Yue Zhao, Chengbang Lu, Xiaopeng Bai, Shangyi Wu, Zeyu Wang, Yuqin Hu, Binxin Liang, Danlei Sun, Yunxiang Zhang, Yingning He, Yi Yang, Shengwen Duan, Taolin Sun, Xinjie Wang, Weijie Lan, Hong Zhang, Yang Luo, Xiangyu Liang   +17 more
wiley   +1 more source