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Systems Toxicology: from basic research to risk assessment
Systems Toxicology is the integration of classical toxicology with quantitative analysis of large networks of molecular and functional changes occurring across multiple levels of biological organization. Society demands increasingly close scrutiny of the
WILKS Martin +35 more
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Ensitrelvir and nirmatrelvir are the two most widely used oral SARS-CoV-2 main protease inhibitors, yet their toxicological profiles have never been compared under a single computational panel.
Gabriel Vinícius Rolim Silva +8 more
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Chemistry Dashboard Data: Abstract Sifter Excel
Sifter Excel data from the CompTox Chemistry Dashboard. The Chemistry Dashboard is part of a suite of dashboards developed by EPA to help evaluate the safety of chemicals. It provides access to a variety of information on over 700,000 chemicals currently
EPA's National Center for Computational Toxicology (5039467)
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Network toxicology and its application in studying exogenous chemical toxicity
With the continuous development of society, a large number of new chemicals are continuously emerging, which presents a challenge to current risk assessment and safety management of chemicals.
Yanli LIN +6 more
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Identifying reliable negative control compounds is essential for determining the sensitivity and specificity of screening assays. However, well-characterized negative controls for developmental neurotoxicity behavioral assays in larval zebrafish (Danio ...
Bridget R. Knapp +4 more
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Microscale Testing in Aquatic Toxicology [PDF]
Bioassays are among the ecotoxicologist's most effective weapons in the evaluation of water quality and the assessment of ecological impacts of effluents, chemicals, discharges, and emissions on the aquatic environment.
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Activation of Metal Complexes With Ultrasound Waves for Targeted Anticancer Therapy
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean +3 more
wiley +1 more source
Fundamentals of Analytical Toxicology
The analytical toxicologist may be required to detect, identify, and in many cases measure a wide variety of compounds in samples from almost any part of the body or in related materials such as residues in syringes or in soil. This book gives principles
Watson, ID +3 more
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Toxicology research for precautionary decision-making and the role of Human & Experimental Toxicology [PDF]
A key aim of toxicology is the prevention of adverse effects due to toxic hazards. Therefore, the dissemination of toxicology research findings must confront two important challenges: one being the lack of information on the vast majority of potentially ...
Grandjean, Philippe
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A manganese single‐atom photocatalyst on functionalised carbon nitride enables selective visible‐light‐driven C(sp2)─H chlorination. DFT‐supported mechanistic studies indicate that photoinduced charge separation activates NCS, while isolated Mn sites stabilize Mn─Cl intermediates at the catalyst interface.
Jaro Vanderghinste +16 more
wiley +1 more source

