Results 81 to 90 of about 1,723,253 (280)

Systems Toxicology: from basic research to risk assessment

open access: yes, 2014
Systems Toxicology is the integration of classical toxicology with quantitative analysis of large networks of molecular and functional changes occurring across multiple levels of biological organization. Society demands increasingly close scrutiny of the
WILKS Martin   +35 more
core   +1 more source

Comparative Evidence-Weighted In Silico Toxicity Profiling of the SARS-CoV-2 Main Protease Inhibitors Ensitrelvir and Nirmatrelvir

open access: yesCOVID
Ensitrelvir and nirmatrelvir are the two most widely used oral SARS-CoV-2 main protease inhibitors, yet their toxicological profiles have never been compared under a single computational panel.
Gabriel Vinícius Rolim Silva   +8 more
doaj   +1 more source

Chemistry Dashboard Data: Abstract Sifter Excel

open access: yes, 2018
Sifter Excel data from the CompTox Chemistry Dashboard. The Chemistry Dashboard is part of a suite of dashboards developed by EPA to help evaluate the safety of chemicals. It provides access to a variety of information on over 700,000 chemicals currently
EPA's National Center for Computational Toxicology (5039467)
core   +1 more source

Network toxicology and its application in studying exogenous chemical toxicity

open access: yes环境与职业医学
With the continuous development of society, a large number of new chemicals are continuously emerging, which presents a challenge to current risk assessment and safety management of chemicals.
Yanli LIN   +6 more
doaj   +1 more source

Utilizing Multiple Behavioral Endpoints to Identify Negative Control Chemicals in a Larval Zebrafish Behavior Assay

open access: yesToxics
Identifying reliable negative control compounds is essential for determining the sensitivity and specificity of screening assays. However, well-characterized negative controls for developmental neurotoxicity behavioral assays in larval zebrafish (Danio ...
Bridget R. Knapp   +4 more
doaj   +1 more source

Microscale Testing in Aquatic Toxicology [PDF]

open access: yes, 1998
Bioassays are among the ecotoxicologist's most effective weapons in the evaluation of water quality and the assessment of ecological impacts of effluents, chemicals, discharges, and emissions on the aquatic environment.

core   +1 more source

Activation of Metal Complexes With Ultrasound Waves for Targeted Anticancer Therapy

open access: yesAngewandte Chemie International Edition, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean   +3 more
wiley   +1 more source

Fundamentals of Analytical Toxicology

open access: yes, 2020
The analytical toxicologist may be required to detect, identify, and in many cases measure a wide variety of compounds in samples from almost any part of the body or in related materials such as residues in syringes or in soil. This book gives principles
Watson, ID   +3 more
core   +1 more source

Toxicology research for precautionary decision-making and the role of Human & Experimental Toxicology [PDF]

open access: yes, 2017
A key aim of toxicology is the prevention of adverse effects due to toxic hazards. Therefore, the dissemination of toxicology research findings must confront two important challenges: one being the lack of information on the vast majority of potentially ...
Grandjean, Philippe
core   +1 more source

Interfacial Mn‐Carbon Nitride Synergy Enables Selective Photocatalytic C─H Chlorination via Single‐Atom Catalysis

open access: yesAngewandte Chemie International Edition, EarlyView.
A manganese single‐atom photocatalyst on functionalised carbon nitride enables selective visible‐light‐driven C(sp2)─H chlorination. DFT‐supported mechanistic studies indicate that photoinduced charge separation activates NCS, while isolated Mn sites stabilize Mn─Cl intermediates at the catalyst interface.
Jaro Vanderghinste   +16 more
wiley   +1 more source

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