Results 131 to 140 of about 613,456 (310)

Time-Series Feature Extraction by Return Map Analysis and Its Application to Bearing-Fault Detection

open access: yesBig Data and Cognitive Computing
Developing new features for time-series characterization is a current challenge in data science and machine learning. In this paper, we propose a new metric based on a simple and efficient algorithm, namely, the return map.
Veronika Ponomareva   +6 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Cross-domain autonomous driving visual segmentation based on enhanced target data learning

open access: yesICT Express
Within the broader context of Information and Communications Technology (ICT), the quest for reliable and scalable visual segmentation methods poses significant challenges, particularly in autonomous driving, where real-world scene complexity requires ...
Chaoyu Rao   +4 more
doaj   +1 more source

CA-Techniken und CIM

open access: yes, 2008
Der Arbeitsbericht gibt zunächst einen Überblick über die technisch orientierten rechnergestützten Komponenten im Rahmen des Computer Integrated Manufacturing (CIM), die sogenannten "CAx-Systeme" oder "CA-Systeme": CAD (Computer Aided Design), CAP ...
Kurbel, K. (Karl)
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Computer aided design at electrotechnics [PDF]

open access: yes, 2008
Tato práce se zabývá problematikou využití moderní výpočetní techniky pro účely podpory projektování v elektrotechnice. V úvodu seznamuje s obecnými základy projektování, důvody a stupni zpracovávaných dokumentací. Následuje kategorizace a rozdělení typů
Tesař, Radek
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Computer-aided space shuttle orbiter wing design study [PDF]

open access: yes
An analytical and experimental investigation has been made to provide a space shuttle orbiter wing design that met the guideline requirements of landing performance, stability, and hypersonic trim for a specified center-of-gravity envelope.
Decker, J. P.   +3 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

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