Results 161 to 170 of about 13,701,591 (243)

Transforming waste plastic into play : an interactive gaming installation utilizing immersive technology

30th International Conference on Computer-Aided Architectural Design Research in Asia (CAADRIA 2025), 22-29 March 2025, The University of Tokyo, JAPAN202505 bcchVersion of RecordOthersPolyU (UGC)PublishedCopyright retained by ...
Lo, TTS, Li, Y, Bao, H, He, Y
core  

<i>N</i>-Myristoyltransferase Inhibition in Parasitic Pathogens: Insights from Computer-Aided Drug Design. [PDF]

Molecules
Campos FFGR, Moura WCDS, Romário-Silva D, Araújo RSA, Morais I, Cortes S, Nogueira F, Nogueira F, Moura RO, Nascimento IJDS.   +9 more
europepmc   +1 more source

Computer-Aided Drug Design Boosts RAS Inhibitor Discovery. [PDF]

Molecules, 2022
Wang G, Bai Y, Cui J, Zong Z, Gao Y, Zheng Z.   +5 more
europepmc   +1 more source

Clinical Variability and Genotype Driven Outcomes in an International Cohort of 14 Pediatric FIG4 Patients

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Biallelic FIG4 variants classically cause distinct conditions characterized by peripheral neuropathy (Charcot‐Marie‐Tooth disease type 4J) or skeletal dysplasia (Yunis‐Varón syndrome). However, central nervous system involvement is increasingly recognized. The prevalence and specific characteristics of movement disorders within FIG4‐
Andrea Gangfuß, Vykuntaraju K. Gowda, Daniel Natera‐de Benito, Pinki Munot, Maria Vanegas, Alejandra Darling, Constanze Reutlinger, Laura Carrera‐Garcia, Gilbert Wunderlich, Heike Kölbel, Burkhard Stüve, David Muhmann, Lucía Monfort Belenguer, Diana‐Gabriela Barca, Viveka Santhosh Reddy C, Varunvenkat M. Srinivasan, Cristina Molina Anguita, Heinz Jungbluth, Hormos Salimi Dafsari, Thomas Rossor, Johann Böhm, Ulrike Schara‐Schmidt, Andreas Roos   +22 more
wiley   +1 more source

Discovery of Highly Potent Noncovalent Inhibitors of SARS-CoV-2 Main Protease through Computer-Aided Drug Design. [PDF]

J Med Chem
Okabe A, Carney DW, Tawada M, Akther T, Aida J, Takagi T, Dougan DR, Leffler AE, Bell JA, Frye L, Hickey ER, Komandla M, Tao W, Selimkhanov J, Yonemori K, Chang E, Saikatendu K, Ochida A.   +17 more
europepmc   +1 more source

Computer-aided drug design for virtual-screening and active-predicting of main protease (M^pro) inhibitors against SARS-CoV-2. [PDF]

Front Pharmacol, 2023
Dai R, Gao H, Su R.
europepmc   +1 more source

Artificial Intelligence–Based Online Symptom Assessment Tools for Systemic Lupus Erythematosus Diagnosis: Patient Perspectives

Arthritis Care &Research, EarlyView.
Objective The objective of this article is to identify perceptions of patients with systemic lupus erythematosus (SLE) regarding artificial intelligence (AI)–based online symptom assessment tools, and the potential of these tools to address diagnostic barriers.
Olivia A. Stein, Jennifer L. F. Lee, Evelyne Vinet, Arielle Mendel, Christian A. Pineau, Fares Kalache, Louis‐Pierre Grenier, Sasha Bernatsky   +7 more
wiley   +1 more source

Investigating the Structural and Functional Consequences of Pathogenic SNPs on Human VEGFA Dimer: Insights from Molecular Dynamics Study

ACS Omega
Rajib Islam, Md. Jahirul Islam, Sadia Jaman, Md. Arafat Hossen, Sayeda Samina Ahmed, Syeda Samira Afrose, Md. Junaid, Md Shahinozzaman, Mohammad A. Halim   +8 more
doaj   +1 more source

A Return to Normality: A Descriptive Qualitative Interview Study Exploring the Patient Experience of Gout Flare Resolution

Arthritis Care &Research, EarlyView.
Objective Although the definition of a gout flare is well established, the state of gout flare resolution has not yet been defined. This study aimed to explore patients’ experiences and perceptions of gout flare resolution. Methods Semistructured interviews were conducted with 24 people with gout, guided by open‐ended questions exploring their ...
Sarah Stewart, Anne Horne, Angelo Gaffo, Lisa K. Stamp, N. Lawrence Edwards, Nicola Dalbeth   +5 more
wiley   +1 more source

Mechanisms of action underlying Shentong Zhuyu decoction based treatment of rheumatoid arthritis using systems biology and computer-aided drug design. [PDF]

Medicine (Baltimore), 2023
Bai S, Han X, Lan Y, Wang H, Wang R, Li L, Song Q, Li A.   +7 more
europepmc   +1 more source