Results 211 to 220 of about 141,530 (234)
Some of the next articles are maybe not open access.
Strategies for Indirect Computer-Aided Drug Design
Pharmaceutical Research, 1993This review is intended to describe some of the methods and procedures used for computer-aided drug design when the structure of the macromolecular target is unknown, as is the case for CNS active drugs. Strategies and methods used in computer-aided design of drugs in such instances must be "indirect," i.e., focusing on the characterization of the ...
G H, Loew, H O, Villar, I, Alkorta
openaire +2 more sources
Computer-Aided Drug Design in Anticancer Drugs
MedScien, 2023The fight against cancer is a significant global health issue, and creating effective anticancer medications is crucial to addressing this challenge. Traditional methods of developing these drugs are time-consuming and require substantial financial investment.
openaire +1 more source
Computer-aided retrometabolic drug design: soft drugs
Expert Opinion on Drug Discovery, 2007Soft drug design approaches aim to design new therapeutic agents that undergo facile, preferentially hydrolytic metabolism to produce inactive metabolites. This approach is general and can be used in essentially any therapeutic area, especially where the desired activity is localized, relatively short-lived or susceptible to easy titration.
openaire +2 more sources
DrugDevCovid19: An Atlas of Anti-COVID-19 Compounds Derived by Computer-Aided Drug Design
Molecules, 2022Jianhong Gan +2 more
exaly
Transforming Drug Design: Innovations in Computer-Aided Discovery for Biosimilar Agents
BioMedInformatics, 2023Hamed Taherdoost, Taherdoost Hamed
exaly
Computer-aided drug design against spike glycoprotein of SARS-CoV-2 to aid COVID-19 treatment
Heliyon, 2020Muhammad Shehroz +2 more
exaly
Computer-Aided Drug Design Applied to Secondary Metabolites as Anticancer Agents
Current Topics in Medicinal Chemistry, 2020Edeíldo Ferreira da Silva-Junior +2 more
exaly