Results 21 to 30 of about 47,108 (219)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Computer Aided Design Applications in Control and Electrical Engineering

open access: yesMeasurement + Control, 1986
This paper was originally presented at a meeting of the Chester Branch of the Institute of Measurement and Control on 23rd February 1984, and was awarded the BIMCAM Ardley Award for the best paper presented to a Local Section in the 1983/84 Session.
A J Hinkins
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

INTEGRASI SOFTWARE CAD-CAM DALAM SISTEM OPERASI MESIN BUBUT CNC

open access: yesJurnal informatika UPGRIS, 2015
Computer Aided Manufacturing (CAM)) adalah sebuah teknologi aplikasi yang menggunakan perangkat lunak komputer dan mesin untuk memfasilitasi dan mengotomatisasi proses manufaktur.
Yuris Setyoadi, Khoiriya Latifah
doaj   +1 more source

R-tree data structure implementation for Computer Aided Engineering (CAE) tools

open access: yesInternational Journal for Simulation and Multidisciplinary Design Optimization, 2021
Searching and handling geometric data are basic requirements of any Computer Aided Engineering application (CAE). Spatial search and local search has greater importance in CAD and CAE applications for reducing the model preparation time.
Shelar Vaibhav   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Spatiotemporal Trajectories of Pedestrian Mobility at the Train Station: evidence of 24 million trajectories

open access: yesScientific Data
Understanding pedestrian movement remains crucial for designing efficient and safe transportation structures such as terminals, stations, or airports. The significance of conducting a granular analysis in pedestrian mobility dynamics research is evident ...
Tomáš Apeltauer   +3 more
doaj   +1 more source

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