Results 61 to 70 of about 385,258 (306)
Computer‐based laboratory simulation: Evaluations of student perceptions [PDF]
, 1996 Providing resources to meet the needs of oil workers who miss blocks of an engineering course was the motivation for producing computer‐based simulations of laboratory equipment. This paper reports on student perceptions of various aspects of the package.
Edward, Norrie, Norrie S. Edward
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The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Genuine lab experiences for students in resource constrained environments: The RealLab with integrated intelligent assessment. [PDF]
, 2008 Laboratory activities are indispensable for developing engineering skills. Computer Aided Learning (CAL) tools can be used to enhance laboratory learning in various ways, the latest approach being the virtual laboratory technique that emulates ...
Chika, I. +7 more
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FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
IEEE Access, 2017 According to the model-driven engineering paradigm, one of the entry requirements when realizing a seamless tool chain for the development of software is the definition of metamodels, to regulate the specification of models, and model transformations ...
Alessio Bucaioni +4 more
doaj +1 more source
18th CAE Computer Conference [PDF]
, 1987 [Abstract]: Computer Aided Engineering (CAE), the application of computers in the broadest sense including Computer Aided Design (CAD) and Computer Aided Manufacture (CAM), is expected to affect virtually every aspect of engineering.
Hall, David, Toleman, Mark
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Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Visual Materials - Video - Camp CAEN Computer Exploration Camp
, 2012 Promotional video describing the unique features and course offerings at Camp CAEN, a computer exploration camp for middle and high school students and sponsored by CAEN and the College of Engineering.
Computer-Aided Engineering Network (CAEN), University of Michigan
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