Results 81 to 90 of about 424,101 (310)

Improving NAVFAC's total quality management of construction drawings with CLIPS [PDF]

A diagnostic expert system to improve the quality of Naval Facilities Engineering Command (NAVFAC) construction drawings and specification is described. C Language Integrated Production System (CLIPS) and computer aided design layering standards are used
Antelman, Albert
core   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Intelligent Support for a Computer Aided Design Optimisation Cycle

Acta Polytechnica, 2006
It is becoming more and more evident that  adding intelligence  to existing computer aids, such as computer aided design systems, can lead to significant improvements in the effective and reliable performance of various engineering tasks, including ...
B. Dolšak, M. Novak, J. Kaljun
doaj  

Computer Aided Process Engineering for Sustainability Analysis of Food Production

Chemical Engineering Transactions, 2015
We propose a dedicated tool that permits the evaluation of food production process sustainability, in particular virgin olive oil process. It is based on an integrated process-product-enterprise (P²E) approach that allows systematically taking into ...
G. Busset, C. Sablayrolles, M. Montrejaud-Vignoles, C. Vialle, J.P. Belaud   +4 more
doaj   +1 more source

Computer-aided engineering and additive manufacturing for bioreactors in tissue engineering: State of the art and perspectives. [PDF]

Biophys Rev (Melville), 2023
Di Gravina GM, Loi G, Auricchio F, Conti M.   +3 more
europepmc   +1 more source

Computer-aided laccase engineering: toward biological oxidation of arylamines [PDF]

, 2016
Oxidation of arylamines, such as aniline, is of high industrial interest and laccases have been proposed as biocata-lysts to replace harsh chemical oxidants.
Acebes, Sandra, Camarero, Susana, De Salas, Felipe, Guallar, Victor, Lucas, Fátima, Martínez, Ángel T., Monza, E., Santiago, G.   +7 more
core   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Computer-aided engineering of staphylokinase toward enhanced affinity and selectivity for plasmin. [PDF]

Comput Struct Biotechnol J, 2022
Nikitin D, Mican J, Toul M, Bednar D, Peskova M, Kittova P, Thalerova S, Vitecek J, Damborsky J, Mikulik R, Fleishman SJ, Prokop Z, Marek M.   +12 more
europepmc   +1 more source

Practical quality control tools for curves and surfaces [PDF]

Curves (geometry) and surfaces created by Computer Aided Geometric Design systems in the engineering environment must satisfy two basic quality criteria: the geometric shape must have the desired engineering properties; and the objects must be ...
Small, Scott G.
core   +1 more source

Molecular modeling for physical property prediction [PDF]

, 2006
Multiscale modeling is becoming the standard approach for process study in a broader framework that promotes computer aided integrated product and process design.
Gerbaud, Vincent, Joulia, Xavier
core