Results 51 to 60 of about 145,245 (295)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Study on Man-machine Design of Armoured Vehicles Operation Space

open access: yesMATEC Web of Conferences, 2018
This paper proposes an improved armoured vehicle control room based on ergonomic theory and computer-aided design technology to create efficiency by improving panel layout and seat design.
Hemin Du, Ting Wang
doaj   +1 more source

Digital Characteristics of Microstructure of Diamond—Silicon Carbide Composites

open access: yesCeramics, 2023
As an example of the implementation of digital materials science approaches based on statistical processing of electron micrographs with the analysis of fractal parameters, the digital characteristics of microstructure of diamond–silicon carbide ceramic ...
Andrey G. Chekuryaev   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Square Root of a Multivector of Clifford Algebras in 3D: A Game with Signs

open access: yesMathematics
An algorithm is presented to extract the square root from a multivector (MV) in real Clifford algebras Clp,q, where n=p+q≤3, in radicals. It is shown that in Cl3,0, Cl1,2, and Cl0,3 algebras, there are up to four isolated square roots in a case of the ...
Arturas Acus, Adolfas Dargys
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Proceedings of the 25th Conference on Formal Methods in Computer-Aided Design, FMCAD 2025

open access: yes
The Conference on Formal Methods in Computer-Aided Design (FMCAD) is an annual conference on the theory and applications of formal methods in hardware and system verification.
Formal Methods in Computer Aided Design
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Computer Assisted Relief Generation - a Survey [PDF]

open access: yes, 2012
In this paper we present an overview of the achievements accomplished to date in the field of computer aided relief generation. We delineate the problem, classify the different solutions, analyze similarities, investigate the evelopment and review the ...
Seidel, Hans-Peter   +17 more
core   +1 more source

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