Results 91 to 100 of about 606,107 (335)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Development of Online Learning Tools Based on Computer Assisted Instruction Material for Newton’s Law of Gravity [PDF]
Fauzi Bakri +3 more
openalex +1 more source
Some breathers and multi-breathers for FPU-type chains
We consider several breather solutions for FPU-type chains that have been found numerically. Using computer-assisted techniques, we prove that there exist true solutions nearby, and in some cases, we determine whether or not the solution is spectrally ...
Arioli, Gianni, Koch, Hans
core +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
A computer assisted proof of the symmetries of least energy nodal\n solutions on squares [PDF]
Ariel Salort, Christophe Troestler
openalex +1 more source
Towards structuring contextual information for workflow-driven surgical assistance functionalities
A workflow-driven cooperative working environment needs to be established in order to successfully unburden the surgeon and the OR staff from technical configuration and information-seeking tasks.
Franke Stefan, Neumuth Thomas
doaj +1 more source
Computer assisted modelling of linear, integer and separable programming problems [PDF]
For mathematical programming (MP) to have greater impact upon the decision making process, MP software systems must offer suitable support in terms of model communication and modelling techniques .
Darby-Dowman, K, Lucas, CA, Mitra, G
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Uncertainty estimation methods are expected to improve the understanding and quality of computer-assisted methods used in medical applications (e.g., neurosurgical interventions, radiotherapy planning), where automated medical image segmentation is ...
Blatti-Moreno, Marcela +6 more
core +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source

