Results 91 to 100 of about 2,559,571 (361)

Acoustic Field Characterization of Medical Array Transducers Based on Unfocused Transmits and Single-Plane Hydrophone Measurements

open access: yesSensors, 2019
Medical ultrasonic arrays are typically characterized in controlled water baths using measurements by a hydrophone, which can be translated with a positioning stage.
Torben Marhenke   +5 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Effectiveness of Computer Assisted Laboratory Instructions:Learning Outcomes Analysis

open access: yes, 2007
This study investigates the impact of computer assisted instructions on learning effectiveness in computer aided design and manufacturing modules which are integral to mechanical engineering related courses.
Abdulrasool, Salah Mahdi   +4 more
core  

09471 Abstracts Collection – Computer-assisted proofs - tools, methods and applications [PDF]

open access: yes, 2010
From 15.11. to 20.11.2009, the Dagstuhl Seminar 09471 ``Computer-assisted proofs - tools, methods and applications '' was held in Schloss Dagstuhl~--~Leibniz Center for Informatics.
Rump, Siegfried M.   +3 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Systems Science and Social Science Foundations of Computer-Assisted Policy Analysis

open access: yes, 2022
S.20-78Originally developed in the technical sciences, computer simulation has over the past decade been increasingly used for the simulation of processes in societal systems and as a tool of policy analysis.
Gruber, Edelgard, Bossel, Hartmut
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Towards structuring contextual information for workflow-driven surgical assistance functionalities

open access: yesCurrent Directions in Biomedical Engineering, 2015
A workflow-driven cooperative working environment needs to be established in order to successfully unburden the surgeon and the OR staff from technical configuration and information-seeking tasks.
Franke Stefan, Neumuth Thomas
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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