Results 101 to 110 of about 602,785 (287)
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
External and Internal Validation of a Computer Assisted Diagnostic Model for Detecting Multi-Organ Mass Lesions in CT images [PDF]
, 2021 Lianyan Xu +6 more
openalex +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Current Directions in Biomedical Engineering, 2015 An essential aspect for workflow management support in operating room environments is the description and visualization of the underlying processes and activities in a machine readable format as Surgical Process Models (SPM).
Neumann Juliane, Neumuth Thomas
doaj +1 more source
Computer assisted interactive resource scheduling system [PDF]
A computer system is reported that effectively schedules complex mission support by processing spacecraft requirements, station capabilities, and ephemeris data in teletype format ready for ...
Gustafson, C. E.
core +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Developing Computer-Assisted Tutorial Instructional Program for Teaching Grammar in Higher Education [PDF]
, 2015 The aims of this research were to: (1) gain information on the existing condition of learning media which are used by lecturers to teach grammar, (2) develop the proper media which is suitable for the students' need and appropriate to teach grammar, and (
Asib, A. (Abdul) +2 more
core
A better proof of the Goldman-Parker conjecture
, 2005 The Goldman-Parker Conjecture classifies the complex hyperbolic C-reflection ideal triangle groups up to discreteness. We proved the Goldman-Parker Conjecture in [Ann. of Math. 153 (2001) 533--598] using a rigorous computer-assisted proof.
Epstein +4 more
core +4 more sources
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Paper # 16: The Effect of Femoral Graft Placement on Tibial Rotation After ACL Reconstruction - Clinical Assessment Using Computer-Assisted Navigation [PDF]
, 2011 R. Barredo +2 more
openalex +1 more source