Results 141 to 150 of about 330,950 (237)

CHARACTERISTICS AND EVALUATION METHODS OF THE CASE TOOLS [PDF]

open access: yes
The acronym CASE – Computer Assisted Software Engineering – is the term used to indicate a collection of methods, tools and processes used in the development of software products with the assistance of the computer ...
Ionel Iacob
core  

Identification of amino acids essential for angulin‐1/3 binding of the tricellular tight junction binder, angubindin‐1

open access: yesFEBS Open Bio, EarlyView.
Angubindin‐1 binds angulin‐1/‐3 at tricellular tight junctions, enhancing intestinal macromolecule permeation. Alanine scanning identified six essential residues (L562, L598, E638, V640, Y643, and K644) of angubindin‐1 critical for binding to angulin‐1/‐3 and permeation‐enhancing activity, providing insights for the development of targeted noninvasive ...
Taiki Kuzu   +8 more
wiley   +1 more source

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

open access: yesFEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová   +11 more
wiley   +1 more source

The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells

open access: yesFEBS Open Bio, EarlyView.
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel   +8 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Multi-Role BPMN Models for the Automatic Generation of Collaborative Checklists to Provide Role-specific Support in the OR

open access: yesCurrent Directions in Biomedical Engineering
The operating room demands well-functioning workflows and optimized communication. Based on the formalization of specific surgical interventions via BPMN, intraoperative checklists can automatically be generated to support the surgical team by the ...
Wiskow René   +5 more
doaj   +1 more source

135: BONE DENSITOMETRY WITH THE AID OF COMPUTER ASSISTED TOMOGRAPHY (CAT) [PDF]

open access: bronze, 1976
G. Ulrich Exner   +5 more
openalex   +1 more source

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