Results 151 to 160 of about 602,785 (287)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Multi-Role BPMN Models for the Automatic Generation of Collaborative Checklists to Provide Role-specific Support in the OR

Current Directions in Biomedical Engineering
The operating room demands well-functioning workflows and optimized communication. Based on the formalization of specific surgical interventions via BPMN, intraoperative checklists can automatically be generated to support the surgical team by the ...
Wiskow René, Junger Denise, Beyersdorffer Patrick, Schaumann Katharina, Klenzner Thomas, Burgert Oliver   +5 more
doaj   +1 more source

The Building Design of Food Enterprises with the Assistance of BIM-assisted Computer

, 2016
Ya Wang
openalex   +1 more source

CHARACTERISTICS AND EVALUATION METHODS OF THE CASE TOOLS [PDF]

The acronym CASE – Computer Assisted Software Engineering – is the term used to indicate a collection of methods, tools and processes used in the development of software products with the assistance of the computer ...
Ionel Iacob
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Bone Marrow Fibrosis Assessed by Computer-Assisted Image Analysis (CIA) is Associated with Poor Risk Cytogenetics and Lower Overall Survival after Allogeneic HSCT for Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS)

, 2018
Said Mohamed, Nasir Bakshi, Mohamed E. Salama, Saleh Al Humaid, Nahlah Al Ghasham, Mona Hassanein, Fahad Al Mohareb, Mahmoud Aljurf, Hazzaa Al Zahrani, Tusneem Elhassan, Emad Ghobashi, Feras Alfraih, Fazal Hussain, Syed Osman Ahmed   +13 more
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Computer Assisted Thermal Complexation Studies of Vanadium with Benzodiazepine Drugs

, 2019
Neeraj Sharma, Vinod Kumar Vashistha, Usha Sharma   +2 more
openalex   +1 more source

Correcting Angular Limb Deformities of Radius-Ulna and Tibia in Nine Dogs Using Computer-Assisted Spider Frame System

, 2023
Zihni MUTLU, Murat KARABAĞLI, Yusuf Altundağ, Svetoslav Stoyanov HRISTOV   +3 more
openalex   +1 more source