Results 151 to 160 of about 550,093 (335)

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

Molecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou, Argyro Roumeliotou, Evangelia Pantazaka, Athanasios‐Nasir Shaukat, Athina Christopoulou, Angelos Koutras, Foteinos‐Ioannis Dimitrakopoulos, Vassilis Georgoulias, Anastasia Xagara, Evangelia Chantzara, Fillipos Koinis, Athanasios Kotsakis, Constantinos Stathopoulos, Galatea Kallergi   +13 more
wiley   +1 more source

Computer-assisted analysis of adenosine triphosphate data [PDF]

, 1976
Carl W. Erkenbrecher, S J Crabtree, L. Harold Stevenson   +2 more
openalex   +1 more source

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

Molecular Oncology, Volume 19, Issue 5, Page 1532-1545, May 2025.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang, Ting Guo, Xiaofang Xing, Xijuan Liu, Xuejun Gan, Yingai Li, Yan Liu, Fei Shan, Zhouqiao Wu, Jiafu Ji, Ziyu Li   +10 more
wiley   +1 more source

Computer-assisted Follow-up Register for the North-East of Scotland [PDF]

, 1970
A. J. Hedley, Anthony Scott, R. D. Weir, J. Crooks   +3 more
openalex   +1 more source

Unraveling epigenetic heterogeneity across gastrointestinal adenocarcinomas through a standardized analytical framework

Molecular Oncology, Volume 19, Issue 4, Page 1117-1131, April 2025.
This study shows that patients with gastrointestinal adenocarcinomas can be stratified into six distinct subtypes based on genome‐scale DNA methylation profiling. This stratification, achieved using a robust analytical framework, aligns with established tumor characteristics and holds potential to support prognostication.
Rita Pinto, Hege Marie Vedeld, Guro Elisabeth Lind, Marine Jeanmougin   +3 more
wiley   +1 more source

Speech synthesis for computer assisted instruction [PDF]

, 1976
William R. Sanders, Gerard V. Benbassat, Robert L. Smith   +2 more
openalex   +1 more source

The CDK12–BRCA1 signaling axis mediates dinaciclib‐associated radiosensitivity through p53‐mediated cellular senescence

Molecular Oncology, Volume 19, Issue 4, Page 1265-1280, April 2025.
Dinaciclib blocks CDK12 activity, leading to downregulation of BRCA1, and probably other proteins involved in homologous recombination, promoting nonhomologous end joining. In this scenario, the presence of ionising radiation triggers a p53‐dependent senescent response that yields increased radiosensitivity. Pan‐cyclin‐dependent‐kinase (CDK) inhibitors
Natalia García Flores, Diego M. Fernández‐Aroca, Cristina Garnés‐García, Andrés Domínguez‐Calvo, Jaime Jiménez‐Suárez, Sebastià Sabater, Pablo Fernández‐Aroca, Ignacio Andrés, Francisco J. Cimas, Guillermo de Cárcer, Borja Belandia, Ignacio Palmero, Pablo Huertas, María José Ruiz‐Hidalgo, Ricardo Sánchez‐Prieto   +14 more
wiley   +1 more source

First experience in employing a complex digital support system accompanied by personal assistance to improve aftercare in patients with stroke or transient ischemic attack – results of the PostStroke-Manager feasibility study

Scientific Reports
Stroke aftercare is widely acknowledged as crucial yet challenging. Digital tools offer a promising strategy to improve aftercare and, thus, patients’ quality of life.
Dominik Michalski, Joseph Classen, Daniela Geisler, Daniela Urban, Max Schreiber, Jean-Baptiste Tylcz, Richard Schmidt, Alexander Prost, Till Handel, Andreas Schneider, Stefan Lippmann, Markus Bleckwenn, Galina Ivanova   +12 more
doaj   +1 more source

COMPUTER-ASSISTED LEARNING: INTRODUCTION AND GENERAL CONSIDERATIONS

, 1969
Ralph Gerard
openalex   +1 more source

Computer assisted tomography in orbital disease. [PDF]

, 1974
J Gawler, M D Sanders, J. W. D. Bull, G. du Boulay, John Marshall   +4 more
openalex   +1 more source